The voice of reflux: A systematic review about acoustic voice analysis in reflux patients

IF 4.1 2区综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES

iScience Pub Date : 2025-09-01 DOI:10.1016/j.isci.2025.113468

Nina Moser , Yves Borbély

{"title":"The voice of reflux: A systematic review about acoustic voice analysis in reflux patients","authors":"Nina Moser , Yves Borbély","doi":"10.1016/j.isci.2025.113468","DOIUrl":null,"url":null,"abstract":"<div><div>We summarize the current literature on acoustic voice analysis in gastroesophageal (GERD) and laryngopharyngeal (LPRD) reflux disease. Literature search on Pubmed and Cochrane Library between 04/-18/12/2023; all study types, keywords “reflux”/“voice”/“analysis”, publication dates between 01/01/2000 and 18/12/2023, only publications dealing with acoustic voice analysis in reflux patients. <em>N</em> = 33 clinical trials found and analyzed. <em>N</em> = 27/33 publications confirm reproducible changes in acoustic voice analyses of reflux patients. Most studies worked with recording of vowel /a/ and used the software Kay Elemetrics MDVP. Most frequently analyzed parameters were fundamental frequency, percent/jitter, percent/shimmer. Results were quite inhomogeneous, not least due to the inconsistent study settings (analysis techniques and software), as well as mainly small, monocentric study designs. But acoustic voice analysis has potential; apart from LPRD patients, general GERD patients have hardly been analyzed and new possibilities are expected with technical advances.</div></div>","PeriodicalId":342,"journal":{"name":"iScience","volume":"28 10","pages":"Article 113468"},"PeriodicalIF":4.1000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"iScience","FirstCategoryId":"103","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2589004225017298","RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MULTIDISCIPLINARY SCIENCES","Score":null,"Total":0}

引用次数: 0

Abstract

We summarize the current literature on acoustic voice analysis in gastroesophageal (GERD) and laryngopharyngeal (LPRD) reflux disease. Literature search on Pubmed and Cochrane Library between 04/-18/12/2023; all study types, keywords “reflux”/“voice”/“analysis”, publication dates between 01/01/2000 and 18/12/2023, only publications dealing with acoustic voice analysis in reflux patients. N = 33 clinical trials found and analyzed. N = 27/33 publications confirm reproducible changes in acoustic voice analyses of reflux patients. Most studies worked with recording of vowel /a/ and used the software Kay Elemetrics MDVP. Most frequently analyzed parameters were fundamental frequency, percent/jitter, percent/shimmer. Results were quite inhomogeneous, not least due to the inconsistent study settings (analysis techniques and software), as well as mainly small, monocentric study designs. But acoustic voice analysis has potential; apart from LPRD patients, general GERD patients have hardly been analyzed and new possibilities are expected with technical advances.

Abstract Image

查看原文本刊更多论文

反流的声音：关于反流患者声学声音分析的系统综述

我们总结了目前关于胃食管（GERD）和喉咽（LPRD）反流疾病的声学语音分析的文献。Pubmed和Cochrane图书馆2023年12月18日的文献检索所有研究类型，关键词“反流”/“声音”/“分析”，发表日期在2000年1月1日至2023年12月18日之间，仅涉及反流患者声学声音分析的出版物。发现并分析了33项临床试验。N = 27/33的出版物证实了反流患者声学分析中可重复的变化。大多数研究使用Kay Elemetrics MDVP软件记录元音/a/。最常分析的参数是基频、百分比/抖动、百分比/闪烁。结果相当不均匀，尤其是由于不一致的研究设置（分析技术和软件），以及主要是小的、单中心的研究设计。但是声音分析是有潜力的；除了LPRD患者外，一般的GERD患者几乎没有被分析过，随着技术的进步，有望有新的可能性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

iScience Multidisciplinary-Multidisciplinary

CiteScore

7.20

自引率

1.70%

发文量

1972

审稿时长

6 weeks

期刊介绍： Science has many big remaining questions. To address them, we will need to work collaboratively and across disciplines. The goal of iScience is to help fuel that type of interdisciplinary thinking. iScience is a new open-access journal from Cell Press that provides a platform for original research in the life, physical, and earth sciences. The primary criterion for publication in iScience is a significant contribution to a relevant field combined with robust results and underlying methodology. The advances appearing in iScience include both fundamental and applied investigations across this interdisciplinary range of topic areas. To support transparency in scientific investigation, we are happy to consider replication studies and papers that describe negative results. We know you want your work to be published quickly and to be widely visible within your community and beyond. With the strong international reputation of Cell Press behind it, publication in iScience will help your work garner the attention and recognition it merits. Like all Cell Press journals, iScience prioritizes rapid publication. Our editorial team pays special attention to high-quality author service and to efficient, clear-cut decisions based on the information available within the manuscript. iScience taps into the expertise across Cell Press journals and selected partners to inform our editorial decisions and help publish your science in a timely and seamless way.