Antibacterial susceptibility pattern of Mycobacterium isolates from Alborz bird's garden: Insights into evolution and transmission dynamics

Q3 Medicine

Indian Journal of Tuberculosis Pub Date : 2025-02-25 DOI:10.1016/j.ijtb.2025.02.017

Niloofar Mobarezpour , Nader Mosavari , Tarokh Arzani Birgani , Alireza Jafari

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引用次数: 0

Abstract

Background and Objectives

This study aimed to isolate and identify Mycobacterium strains from the bird population at Alborz Bird Park, as well as from personnel working in the vicinity. Mycobacterium is a historically significant zoonotic pathogen that poses a serious threat to both humans and various bird species.

Materials and Methods

A total of ninety samples of bird feces from different species were collected from CHAMRAN Bird's Park in Alborz province. These samples underwent decontamination, culture, antibacterial susceptibility testing, and PCR analysis.

Results

PCR analysis revealed that 33 out of 42 suspected Mycobacterium isolates from birds tested positive for the Mycobacterium genus. No Mycobacterium tuberculosis complex was detected. The presence of Mycobacterium avium complex was confirmed in 21 isolates, and 16 samples were identified as Mycobacterium avium subsp. avium. Additionally, 12 isolates were identified as non-tuberculous mycobacteria (NTMs).

Conclusion

The presence of Mycobacterium avium complex and non-tuberculous mycobacteria in the bird population highlights the increasing prevalence of NTM infections, particularly in regions with effective tuberculosis control programs. Mycobacterium infections represent a significant threat to individuals with AIDS, ranking as the second leading cause of infectious mortality in this population.

查看原文本刊更多论文

从Alborz鸟类花园分离的分枝杆菌的抗菌敏感性模式：对进化和传播动力学的见解。

背景和目的：本研究旨在从Alborz鸟类公园的鸟类种群以及附近工作人员中分离和鉴定分枝杆菌菌株。分枝杆菌是一种历史上重要的人畜共患病原体，对人类和各种鸟类都构成严重威胁。材料与方法：在阿尔布尔斯省CHAMRAN鸟类公园收集了90份不同种类的鸟类粪便样本。这些样品进行了去污、培养、抗菌药敏试验和PCR分析。结果：PCR分析显示，42株疑似禽类分枝杆菌分离株中有33株分枝杆菌属检测呈阳性。未检出结核分枝杆菌复合体。21株分离物中存在禽分枝杆菌复合体，其中16份标本为禽分枝杆菌亚种。鸟结核。此外，12株分离株被鉴定为非结核分枝杆菌（ntm）。结论：禽分枝杆菌复合体和非结核分枝杆菌在鸟类种群中的存在，突出了NTM感染的患病率不断上升，特别是在结核病控制规划有效的地区。分枝杆菌感染对艾滋病患者构成重大威胁，是该人群感染性死亡的第二大原因。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Indian Journal of Tuberculosis Medicine-Infectious Diseases

CiteScore

2.80

自引率

0.00%

发文量

103

期刊介绍： Indian Journal of Tuberculosis (IJTB) is an international peer-reviewed journal devoted to the specialty of tuberculosis and lung diseases and is published quarterly. IJTB publishes research on clinical, epidemiological, public health and social aspects of tuberculosis. The journal accepts original research articles, viewpoints, review articles, success stories, interesting case series and case reports on patients suffering from pulmonary, extra-pulmonary tuberculosis as well as other respiratory diseases, Radiology Forum, Short Communications, Book Reviews, abstracts, letters to the editor, editorials on topics of current interest etc. The articles published in IJTB are a key source of information on research in tuberculosis. The journal is indexed in Medline