Brucella Infections in Camels and Abattoir Workers in the United Arab Emirates: One Health-Based Seroepidemiological and Molecular Insights

IF 3 2区农林科学 Q2 INFECTIOUS DISEASES

Transboundary and Emerging Diseases Pub Date : 2025-09-19 DOI:10.1155/tbed/7748638

Gobena Ameni, Aboma Zewude, Berecha Bayissa, Abdallah A. Albizreh, Naeema Alhosani, Meera Saeed Alkalbani, Mohamed Moustafa Abdelhalim, Assem Sobhi Abdelazim, Rafeek Aroul Koliyan, Kaltham Kayaf, Mervat Mari Al Nuaimat, Robert Barigye, Balázs Ádám, Mohamud Sheek-Hussein, Guangzhi Zhang, Yassir Mohammed Eltahir, Markos Tibbo

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Abstract

Brucellosis remains a critical zoonotic disease affecting livestock productivity and human health, especially in regions where intensive livestock husbandry is practiced. In the United Arab Emirates (UAE), camels contribute economically and culturally through meat, milk, and racing, yet data on brucellosis in camels and its zoonotic risk remain limited. This cross-sectional study aimed to determine the seroprevalence and molecular detection of Brucella species in camels and abattoir workers in the Emirate of Abu Dhabi, UAE. A total of 356 camels from 102 herds, 368 slaughter camels, and 86 abattoir workers were included. Competitive enzyme-linked immunosorbent assay (cELISA) was used for antibody detection, while species-specific quantitative PCR (qPCR) targeted Brucella abortus, Brucella melitensis, and Brucella ovis in seropositive samples. Herd-level seroprevalence was 10.8% (95% CI: 5.5%–18.5%) and significantly associated with herd size (p < 0.05). Animal seroprevalence was 5.9% (95% confidence level [CI]: 3.7%–8.9%) in field camels and 3.0% (95% CI: 1.51%–5.30%) in slaughtered camels. Seven abattoir workers (8.1%) were seropositive, with butchers at greater risk. By species, B. ovis, B. abortus and B. melitensis were detected in camels, while only B. ovis and B. abortus were in abattoir workers. These findings indicate ongoing zoonotic risks in abattoir settings and support integrated One Health surveillance and control strategies.

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阿拉伯联合酋长国骆驼和屠宰场工人的布鲁氏菌感染：一种基于健康的血清流行病学和分子见解

布鲁氏菌病仍然是一种严重的人畜共患疾病，影响牲畜生产力和人类健康，特别是在实行集约化畜牧业的地区。在阿拉伯联合酋长国（UAE），骆驼通过肉类、牛奶和赛马为经济和文化做出贡献，但关于骆驼中的布鲁氏菌病及其人畜共患风险的数据仍然有限。本横断面研究旨在确定布鲁氏菌在阿联酋阿布扎比酋长国的骆驼和屠宰场工人中的血清阳性率和分子检测。调查对象包括102个畜群356头骆驼、368头屠宰骆驼和86名屠宰场工人。抗体检测采用竞争性酶联免疫吸附法（cELISA），血清阳性样品采用物种特异性定量PCR （qPCR）检测流产布鲁氏菌、melitensis布鲁氏菌和ovis布鲁氏菌。群体水平血清阳性率为10.8% (95% CI: 5.5%-18.5%)，与群体规模显著相关（p < 0.05）。野外骆驼的动物血清阳性率为5.9%(95%置信水平[CI]: 3.7% ~ 8.9%)，屠宰骆驼的动物血清阳性率为3.0% （95% CI: 1.51% ~ 5.30%）。7名屠宰场工人（8.1%）血清呈阳性，屠夫的风险更大。按种类划分，在骆驼中检出卵双球菌、流产双球菌和melitensis，在屠宰场工人中仅检出卵双球菌和流产双球菌。这些发现表明在屠宰场环境中存在人畜共患病风险，并支持“同一个健康”综合监测和控制战略。

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来源期刊

Transboundary and Emerging Diseases 农林科学-传染病学

CiteScore

8.90

自引率

9.30%

发文量

350

审稿时长

1 months

期刊介绍： Transboundary and Emerging Diseases brings together in one place the latest research on infectious diseases considered to hold the greatest economic threat to animals and humans worldwide. The journal provides a venue for global research on their diagnosis, prevention and management, and for papers on public health, pathogenesis, epidemiology, statistical modeling, diagnostics, biosecurity issues, genomics, vaccine development and rapid communication of new outbreaks. Papers should include timely research approaches using state-of-the-art technologies. The editors encourage papers adopting a science-based approach on socio-economic and environmental factors influencing the management of the bio-security threat posed by these diseases, including risk analysis and disease spread modeling. Preference will be given to communications focusing on novel science-based approaches to controlling transboundary and emerging diseases. The following topics are generally considered out-of-scope, but decisions are made on a case-by-case basis (for example, studies on cryptic wildlife populations, and those on potential species extinctions): Pathogen discovery: a common pathogen newly recognised in a specific country, or a new pathogen or genetic sequence for which there is little context about — or insights regarding — its emergence or spread. Prevalence estimation surveys and risk factor studies based on survey (rather than longitudinal) methodology, except when such studies are unique. Surveys of knowledge, attitudes and practices are within scope. Diagnostic test development if not accompanied by robust sensitivity and specificity estimation from field studies. Studies focused only on laboratory methods in which relevance to disease emergence and spread is not obvious or can not be inferred (“pure research” type studies). Narrative literature reviews which do not generate new knowledge. Systematic and scoping reviews, and meta-analyses are within scope.