Hidden placental damage in stillbirths with idiopathic polyhydramnios

IF 2 3区医学 Q2 OBSTETRICS & GYNECOLOGY

Early human development Pub Date : 2025-09-12 DOI:10.1016/j.earlhumdev.2025.106393

Laura Avagliano , Martina Benuzzi , Francesca Monari , Gaetano Bulfamante

引用次数: 0

Abstract

Idiopathic polyhydramnios is clinically linked to stillbirth; however, its placental histopathology remains poorly characterized. This is the first study analyzing placentas from stillbirths with idiopathic polyhydramnios, revealing frequent lesions of fetal and maternal vascular malperfusion. Findings support a previously unrecognized role of placental dysfunction in fetal compromise.

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特发性羊水过多死产的隐性胎盘损伤

特发性羊水过多在临床上与死产有关；然而，其胎盘组织病理学特征仍然很差。这是第一个分析特发性羊水过多死产胎盘的研究，揭示了胎儿和母体血管灌注不良的频繁病变。研究结果支持了先前未被认识到的胎盘功能障碍在胎儿损害中的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Early human development 医学-妇产科学

CiteScore

4.40

自引率

4.00%

发文量

100

审稿时长

46 days

期刊介绍： Established as an authoritative, highly cited voice on early human development, Early Human Development provides a unique opportunity for researchers and clinicians to bridge the communication gap between disciplines. Creating a forum for the productive exchange of ideas concerning early human growth and development, the journal publishes original research and clinical papers with particular emphasis on the continuum between fetal life and the perinatal period; aspects of postnatal growth influenced by early events; and the safeguarding of the quality of human survival. The first comprehensive and interdisciplinary journal in this area of growing importance, Early Human Development offers pertinent contributions to the following subject areas: Fetology; perinatology; pediatrics; growth and development; obstetrics; reproduction and fertility; epidemiology; behavioural sciences; nutrition and metabolism; teratology; neurology; brain biology; developmental psychology and screening.