Fluorescent Sensor Based on Stable Cd(II) Metal–Organic Framework for Rapid and Visual Detection of Tetracycline Antibiotics in Water

IF 3.4 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Crystal Growth & Design Pub Date : 2025-09-01 DOI:10.1021/acs.cgd.5c00597

Wenqiu Qi, Ziqing Zhang, Yunfang Zhao, Yangxingyu Ye, Lian Chen*, Feilong Jiang and Maochun Hong*,

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引用次数: 0

Abstract

Antibiotics, widely used in the fields of medicine, animal husbandry, aquaculture, and agriculture, are ubiquitously present in water systems, posing a serious threat to the environment and human health. It is essential to develop a fast, sensitive, and straightforward analytical method for sensing antibiotics in aqueous solution. In this work, a 3D luminescent metal–organic framework (MOF), named Cd-BTDI, has been synthesized, featuring high structural stability in water. Its intense green luminescence with an emission peak at 509 nm is quite stable in aqueous and common organic solvents, providing a good foundation to fabricate a potential chemical sensor. Cd-BTDI exhibits selective and sensitive detection performance for tetracycline (TC) and oxytetracycline (OTC) antibiotics with fast response and good anti-interference. The limits of detection (LODs) for TC and OTC are 0.071 and 0.062 μΜ, respectively. By introducing the commercially available polymer poly(methyl methacrylate), a reusable sensing film can be fabricated for the on-site visual detection of trace tetracycline antibiotics. In addition, Cd-BTDI can detect tetracycline antibiotics in three kinds of typical real water matrices (tap, lake, and river water), showing great potential for practical uses.

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基于稳定Cd（II）金属-有机骨架的荧光传感器用于水中四环素类抗生素的快速视觉检测

抗生素广泛应用于医药、畜牧、水产养殖和农业等领域，在水体中无处不在，对环境和人类健康构成严重威胁。开发一种快速、灵敏、直观的检测水溶液中抗生素的分析方法是十分必要的。在这项工作中，合成了一种三维发光金属有机框架（MOF），命名为Cd-BTDI，在水中具有很高的结构稳定性。它的强烈绿色发光在509 nm处有一个发射峰，在水和常见的有机溶剂中非常稳定，为制造潜在的化学传感器提供了良好的基础。Cd-BTDI对四环素（TC）和土霉素（OTC）抗菌药物的检测具有选择性好、灵敏度高、响应快、抗干扰性好等特点。TC和OTC的检出限分别为0.071和0.062 μΜ。通过引入市售聚合物聚甲基丙烯酸甲酯，制备了一种可重复使用的传感膜，用于痕量四环素类抗生素的现场视觉检测。此外，Cd-BTDI可在自来水、湖水和河水三种典型真实水基质中检测四环素类抗生素，具有很大的实际应用潜力。

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来源期刊

Crystal Growth & Design 化学-材料科学：综合

CiteScore

6.30

自引率

10.50%

发文量

650

审稿时长

1.9 months

期刊介绍： The aim of Crystal Growth & Design is to stimulate crossfertilization of knowledge among scientists and engineers working in the fields of crystal growth, crystal engineering, and the industrial application of crystalline materials. Crystal Growth & Design publishes theoretical and experimental studies of the physical, chemical, and biological phenomena and processes related to the design, growth, and application of crystalline materials. Synergistic approaches originating from different disciplines and technologies and integrating the fields of crystal growth, crystal engineering, intermolecular interactions, and industrial application are encouraged.