Re: “Severe angiostrongyliasis with neuropsychiatric symptoms in vulnerable adults: Early diagnosis via next-generation sequencing and successful treatment”

IF 4 3区 医学 Q1 INFECTIOUS DISEASES
Nathkapach Kaewpitoon Rattanapitoon, Chutharat Thanchonnang, Patpicha Arunsarn, Schawanya Kaewpitoon Rattanapitoon
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引用次数: 0

Abstract

Tang et al. (2025) report on two cases of neuroangiostrongyliasis in vulnerable adults, diagnosed via metagenomic next-generation sequencing (mNGS). We highlight the clinical value of mNGS in detecting atypical presentations, particularly in patients without eosinophilia or classic meningitic signs. While mNGS demonstrates diagnostic potential, its limitations and feasibility in low-resource settings must be acknowledged. We propose a contextualized approach integrating mNGS with cost-effective tools like LAMP and rapid antigen tests, especially for underserved populations.The commentary also calls attention to the risk of underdiagnosed parasitic CNS infections in socioeconomically vulnerable groups and urges broader diagnostic preparedness and targeted surveillance.
回复:“易感成人伴有神经精神症状的严重血管圆线虫病:通过下一代测序进行早期诊断和成功治疗”。
Tang等人(2025)报道了两例易感成人神经血管线虫病,通过新一代宏基因组测序(mNGS)诊断。我们强调了mNGS在检测非典型表现方面的临床价值,特别是在没有嗜酸性粒细胞增多症或经典脑膜炎症状的患者中。虽然mNGS显示出诊断潜力,但必须承认其在低资源环境下的局限性和可行性。我们建议将mNGS与LAMP和快速抗原检测等具有成本效益的工具结合起来,特别是针对服务不足的人群。该评论还呼吁关注社会经济弱势群体中寄生虫性中枢神经系统感染诊断不足的风险,并敦促更广泛的诊断准备和有针对性的监测。
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来源期刊
Journal of Infection and Public Health
Journal of Infection and Public Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH -INFECTIOUS DISEASES
CiteScore
13.10
自引率
1.50%
发文量
203
审稿时长
96 days
期刊介绍: The Journal of Infection and Public Health, first official journal of the Saudi Arabian Ministry of National Guard Health Affairs, King Saud Bin Abdulaziz University for Health Sciences and the Saudi Association for Public Health, aims to be the foremost scientific, peer-reviewed journal encompassing infection prevention and control, microbiology, infectious diseases, public health and the application of healthcare epidemiology to the evaluation of health outcomes. The point of view of the journal is that infection and public health are closely intertwined and that advances in one area will have positive consequences on the other. The journal will be useful to all health professionals who are partners in the management of patients with communicable diseases, keeping them up to date. The journal is proud to have an international and diverse editorial board that will assist and facilitate the publication of articles that reflect a global view on infection control and public health, as well as emphasizing our focus on supporting the needs of public health practitioners. It is our aim to improve healthcare by reducing risk of infection and related adverse outcomes by critical review, selection, and dissemination of new and relevant information in the field of infection control, public health and infectious diseases in all healthcare settings and the community.
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