Factors associated with early seizure in patients with cerebral arteriovenous malformations

IF 1.8 4区 医学 Q3 CLINICAL NEUROLOGY
Prut Koonalintip , Aurakoch Kanjana-opas , Jarudetch Wichaitum , Rujimas Khumtong , Suwanna Setthawatcharawanich , Pornchai Sathirapanya , Rattana Leelawattana , Pat Korathanakhun
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引用次数: 0

Abstract

This retrospective cohort study aimed to identify factors associated with early seizure (ES) in patients with cerebral arteriovenous malformations (AVMs). Patients diagnosed with cerebral AVMs between 2002 and 2023 were enrolled. Clinical and seizure characteristics, radiographic findings, and clinical outcomes were compared between the ES and non-seizure groups. Factors with p-values < 0.05 in univariate analyses were further analyzed using a multivariable logistic regression model to identify independent factors associated with ES. The incidence of ES was 39.81 % among 309 patients with cerebral AVMs. Focal seizure semiology was recorded in 77 patients (62.60 %), and the rest were considered motor tonic–clonic seizures with unknown onset. Long pial venous drainage (adjusted odds ratio [aOR] 12.015, 95 % confidence interval [CI] 5.325–30.018, p = 0.038) and adjacent cortical edema (aOR 3.112, 95 % CI 1.825–20.125, p = 0.014) were independent associated factors with ES, whereas the focal neurological deficit showed a reversed association (aOR 0.063, 95 % CI 0.011–0.202, p = 0.028). In conclusion, the long pial venous drainage and the adjacent cortical edema were independently associated with ES in patients with cerebral AVMs.
脑动静脉畸形患者早期癫痫发作的相关因素。
本回顾性队列研究旨在确定与脑动静脉畸形(AVMs)患者早期癫痫发作(ES)相关的因素。研究人员招募了2002年至2023年间诊断为脑动静脉畸形的患者。比较癫痫发作组和非癫痫发作组的临床和发作特征、影像学表现和临床结果。具有p值的因子
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Clinical Neuroscience
Journal of Clinical Neuroscience 医学-临床神经学
CiteScore
4.50
自引率
0.00%
发文量
402
审稿时长
40 days
期刊介绍: This International journal, Journal of Clinical Neuroscience, publishes articles on clinical neurosurgery and neurology and the related neurosciences such as neuro-pathology, neuro-radiology, neuro-ophthalmology and neuro-physiology. The journal has a broad International perspective, and emphasises the advances occurring in Asia, the Pacific Rim region, Europe and North America. The Journal acts as a focus for publication of major clinical and laboratory research, as well as publishing solicited manuscripts on specific subjects from experts, case reports and other information of interest to clinicians working in the clinical neurosciences.
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