{"title":"Epoxy Resin Allergy: prevalence and clinical spectrum in a regional population in the Southwest of England.","authors":"Peter Phillips, Preshita Divekar","doi":"10.1093/ced/llaf424","DOIUrl":null,"url":null,"abstract":"<p><p>Epoxy resins, commonly in adhesives, cause occupational allergic contact dermatitis, particularly among male tradesmen. Diglycidyl ether of bisphenol A (DGEBA) is the screening agent for epoxy allergy in the British and European Baseline Series. Recent reports highlight new non-occupational sources of sensitisation in women engaged in craft hobbies. We investigated whether similar trends are emerging in our region. We retrospectively analysed our clinic's patch test data for a 13-year period (2009-2022). Of 2445 patients tested, 15 (0.6%) were sensitised to DGEBA; males 9 (1.2%), females 6 (0.4%). 8 of 10 (80%) sensitized individuals with known relevance were exposed occupationally, 3 of whom had airborne exposure. To be included in the baseline series, an allergen must patch test positive in ≥ 0.5% of consecutively tested patients. Our findings confirm that DGEBA remains a relevant allergen, supporting its continued inclusion. No cases of non-occupational sensitisation from new sources were identified.</p>","PeriodicalId":10324,"journal":{"name":"Clinical and Experimental Dermatology","volume":" ","pages":""},"PeriodicalIF":2.8000,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical and Experimental Dermatology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/ced/llaf424","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DERMATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Epoxy resins, commonly in adhesives, cause occupational allergic contact dermatitis, particularly among male tradesmen. Diglycidyl ether of bisphenol A (DGEBA) is the screening agent for epoxy allergy in the British and European Baseline Series. Recent reports highlight new non-occupational sources of sensitisation in women engaged in craft hobbies. We investigated whether similar trends are emerging in our region. We retrospectively analysed our clinic's patch test data for a 13-year period (2009-2022). Of 2445 patients tested, 15 (0.6%) were sensitised to DGEBA; males 9 (1.2%), females 6 (0.4%). 8 of 10 (80%) sensitized individuals with known relevance were exposed occupationally, 3 of whom had airborne exposure. To be included in the baseline series, an allergen must patch test positive in ≥ 0.5% of consecutively tested patients. Our findings confirm that DGEBA remains a relevant allergen, supporting its continued inclusion. No cases of non-occupational sensitisation from new sources were identified.
期刊介绍:
Clinical and Experimental Dermatology (CED) is a unique provider of relevant and educational material for practising clinicians and dermatological researchers. We support continuing professional development (CPD) of dermatology specialists to advance the understanding, management and treatment of skin disease in order to improve patient outcomes.