{"title":"Graphene-based Surface Plasmon Resonance Biosensor Design Using Square-shaped Metamaterial Resonators for Blood Cancer Detection","authors":"Osamah Alsalman","doi":"10.1007/s11468-024-02652-3","DOIUrl":null,"url":null,"abstract":"<div><p>This study presents a highly sensitive sensor, specifically designed with a unique structure and advanced materials, including graphene and metamaterials, to enhance early detection of blood cancer. The sensor’s structure is meticulously optimized, with graphene serving as a resonating layer and metamaterials integrated to amplify its performance. These materials, combined with the carefully configured structural parameters, create a sensor with superior sensitivity and efficiency. Additionally, adjustments to the angle of light incidence are explored to examine their influence on detection accuracy, further enhancing the sensor’s capabilities. Through this optimized design, the sensor gets an impressive sensitivity of 2143 nm/RIU, making it highly effective for detecting subtle refractive index changes associated with blood cancer biomarkers. Early detection of blood cancer, a condition that can be life-threatening if diagnosed late, is crucial for improving patient outcomes. This sensor, with its high sensitivity and optimized structural design, provides an efficient and powerful tool for early-stage blood cancer diagnosis.</p></div>","PeriodicalId":736,"journal":{"name":"Plasmonics","volume":"20 9","pages":"6963 - 6973"},"PeriodicalIF":4.3000,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Plasmonics","FirstCategoryId":"101","ListUrlMain":"https://link.springer.com/article/10.1007/s11468-024-02652-3","RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
引用次数: 0
Abstract
This study presents a highly sensitive sensor, specifically designed with a unique structure and advanced materials, including graphene and metamaterials, to enhance early detection of blood cancer. The sensor’s structure is meticulously optimized, with graphene serving as a resonating layer and metamaterials integrated to amplify its performance. These materials, combined with the carefully configured structural parameters, create a sensor with superior sensitivity and efficiency. Additionally, adjustments to the angle of light incidence are explored to examine their influence on detection accuracy, further enhancing the sensor’s capabilities. Through this optimized design, the sensor gets an impressive sensitivity of 2143 nm/RIU, making it highly effective for detecting subtle refractive index changes associated with blood cancer biomarkers. Early detection of blood cancer, a condition that can be life-threatening if diagnosed late, is crucial for improving patient outcomes. This sensor, with its high sensitivity and optimized structural design, provides an efficient and powerful tool for early-stage blood cancer diagnosis.
期刊介绍:
Plasmonics is an international forum for the publication of peer-reviewed leading-edge original articles that both advance and report our knowledge base and practice of the interactions of free-metal electrons, Plasmons.
Topics covered include notable advances in the theory, Physics, and applications of surface plasmons in metals, to the rapidly emerging areas of nanotechnology, biophotonics, sensing, biochemistry and medicine. Topics, including the theory, synthesis and optical properties of noble metal nanostructures, patterned surfaces or materials, continuous or grated surfaces, devices, or wires for their multifarious applications are particularly welcome. Typical applications might include but are not limited to, surface enhanced spectroscopic properties, such as Raman scattering or fluorescence, as well developments in techniques such as surface plasmon resonance and near-field scanning optical microscopy.