Au/MnO2 Featuring Efficient Oxidase-mimic Activity at Neutral pH: Toward Portable Dual-modal Sensor for sulfide detection integrated with smartphone

IF 5.1 3区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Nanoscale Pub Date : 2025-09-20 DOI:10.1039/d5nr01766a

Mi Li, Haorong Cheng, Yang Song, Xinxin Shi, Tongxiang Li, Yan Chen, Zhao Li, Lin Tian

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引用次数: 0

Abstract

The rapid detection of sulfide compounds including glutathione (GSH) and Na2S2O8 is of great interest because they play an essential role in the process of food processing. Here, we design a colorimetric/smartphone dual-mode sensing platform to detect GSH and Na2S2O8 simultaneously, depending on gold nanoparticle-decorated MnO2 nanosheets (Au/MnO2 NSs). Because of the distinct structure, Au/MnO2 possesses superior catalytic activity similar to native oxidase capable of catalysing the directly oxidation of 3,3’,5,5’-tetramethylbenzidine (TMB) under near-neutral pH conditions. Meanwhile, this catalytic reaction results in an obvious color change or the solution, which senses GSH and Na2S2O8 through redox and diazotization reactions. The designed sensor enables value-assisted and visual determination of GSH and Na2S2O8 with limits of detection of 2.3 nM. Based on the dual-modal sensing system, a smartphone-mediated “all-in-one” sensing platform is designed to realize the real-time and intelligent monitoring of GSH and Na2S2O8. This work provides a new avenue to construct multifunctional sensors to achieve the visualization and portable determination of sulfide compounds.

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Au/MnO2在中性pH下具有高效的氧化酶模拟活性：与智能手机集成的便携式硫化物检测双峰传感器

由于谷胱甘肽（GSH）和Na2S2O8等硫化物在食品加工过程中起着至关重要的作用，因此对它们的快速检测具有重要的意义。在这里，我们设计了一个比色/智能手机双模式传感平台，同时检测GSH和Na2S2O8，这取决于金纳米颗粒修饰的MnO2纳米片（Au/MnO2 NSs）。由于其独特的结构，Au/MnO2具有与天然氧化酶相似的优越的催化活性，能够在接近中性的pH条件下催化3,3 ',5,5 ' -四甲基联苯胺（TMB）的直接氧化。同时，该催化反应使溶液发生明显的颜色变化，通过氧化还原和重氮化反应感应GSH和Na2S2O8。所设计的传感器可实现GSH和Na2S2O8的值辅助和视觉测定，检测限为2.3 nM。基于双模态传感系统，设计了智能手机介导的“一体化”传感平台，实现对GSH和Na2S2O8的实时智能监测。本工作为构建多功能传感器以实现硫化物的可视化和便携式测定提供了新的途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nanoscale CHEMISTRY, MULTIDISCIPLINARY-NANOSCIENCE & NANOTECHNOLOGY

CiteScore

12.10

自引率

3.00%

发文量

1628

审稿时长

1.6 months

期刊介绍： Nanoscale is a high-impact international journal, publishing high-quality research across nanoscience and nanotechnology. Nanoscale publishes a full mix of research articles on experimental and theoretical work, including reviews, communications, and full papers.Highly interdisciplinary, this journal appeals to scientists, researchers and professionals interested in nanoscience and nanotechnology, quantum materials and quantum technology, including the areas of physics, chemistry, biology, medicine, materials, energy/environment, information technology, detection science, healthcare and drug discovery, and electronics.