{"title":"Exceptional high number of IPD cases in winter season 2024–2025 in Belgium in concomitance with rise in vaccine serotypes","authors":"Lize Cuypers , Cato Dambre , Stefanie Desmet","doi":"10.1016/j.vaccine.2025.127763","DOIUrl":null,"url":null,"abstract":"<div><div>Following lifting of containment measures post-COVID, the number of invasive pneumococcal disease (IPD) infections continued to increase, reaching a record number last winter season 2024–2025 in Belgium. This exceptional increase is largely due to high numbers in (older) adults, and mainly an increase of vaccine serotype IPD. Over 95 % of IPD cases last winter could theoretically be prevented by vaccination. Cases of serotypes 12F, 14 and 4 were three or more times higher compared to pre-COVID winter season 2019–2020.</div></div>","PeriodicalId":23491,"journal":{"name":"Vaccine","volume":"64 ","pages":"Article 127763"},"PeriodicalIF":4.5000,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Vaccine","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0264410X25010606","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Following lifting of containment measures post-COVID, the number of invasive pneumococcal disease (IPD) infections continued to increase, reaching a record number last winter season 2024–2025 in Belgium. This exceptional increase is largely due to high numbers in (older) adults, and mainly an increase of vaccine serotype IPD. Over 95 % of IPD cases last winter could theoretically be prevented by vaccination. Cases of serotypes 12F, 14 and 4 were three or more times higher compared to pre-COVID winter season 2019–2020.
期刊介绍:
Vaccine is unique in publishing the highest quality science across all disciplines relevant to the field of vaccinology - all original article submissions across basic and clinical research, vaccine manufacturing, history, public policy, behavioral science and ethics, social sciences, safety, and many other related areas are welcomed. The submission categories as given in the Guide for Authors indicate where we receive the most papers. Papers outside these major areas are also welcome and authors are encouraged to contact us with specific questions.