Lindsay G Cowell, Scott Christley, Felix Breden, Kevin A Burns, Brian D Corrie, William D Lees, James A Overton, Bjoern Peters, Eve Richardson, Krishna M Roskin, Lonneke Scheffer, Randi Vita, Corey T Watson, Gur Yaari
{"title":"The Adaptive Immune Receptor Repertoire Knowledge Commons: An invitation to the community.","authors":"Lindsay G Cowell, Scott Christley, Felix Breden, Kevin A Burns, Brian D Corrie, William D Lees, James A Overton, Bjoern Peters, Eve Richardson, Krishna M Roskin, Lonneke Scheffer, Randi Vita, Corey T Watson, Gur Yaari","doi":"10.1016/j.cels.2025.101401","DOIUrl":null,"url":null,"abstract":"<p><p>Sequencing data elucidating adaptive immune receptor (AIR) repertoires, genomic loci encoding AIR genes, and AIR antigens are hosted in siloed repositories, limiting integrative analyses. We are in the process of creating the AIR Repertoire Knowledge Commons (AKC) by merging data from community-backed repositories and applying knowledge-generation algorithms to integrate and enrich data and metadata.</p>","PeriodicalId":93929,"journal":{"name":"Cell systems","volume":"16 9","pages":"101401"},"PeriodicalIF":7.7000,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cell systems","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.cels.2025.101401","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Sequencing data elucidating adaptive immune receptor (AIR) repertoires, genomic loci encoding AIR genes, and AIR antigens are hosted in siloed repositories, limiting integrative analyses. We are in the process of creating the AIR Repertoire Knowledge Commons (AKC) by merging data from community-backed repositories and applying knowledge-generation algorithms to integrate and enrich data and metadata.
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