The Effect of Exercise on Asthma in Children: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

IF 4.6 2区医学 Q1 ALLERGY

Current Allergy and Asthma Reports Pub Date : 2025-09-19 DOI:10.1007/s11882-025-01219-4

Zhenghui Zha, Yuli Zhang, Cuiyun Tian, Dongxiang Huang, Tuming Shen, Songtao Wang

{"title":"The Effect of Exercise on Asthma in Children: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.","authors":"Zhenghui Zha, Yuli Zhang, Cuiyun Tian, Dongxiang Huang, Tuming Shen, Songtao Wang","doi":"10.1007/s11882-025-01219-4","DOIUrl":null,"url":null,"abstract":"Purpose of review: Asthma is a heterogeneous respiratory condition and a common childhood disease. The effects of exercise on childhood asthma have not been fully clarified. This study aims to systematically evaluate the impact of exercise on children with asthma, specifically examining lung function, exercise capacity, airway inflammation, and health-related quality of life (HRQoL).Recent findings: 13 randomized controlled trials (RCTs) involving 673 children with asthma, with a mean age ranging from 7.3 to 14 years, were included. The results of the meta-analysis showed that exercise can improve the six-minute walk test (6MWT) distance and the pediatric asthma quality of life questionnaire (PAQLQ) scores in children with asthma but cannot reduce the fractional exhaled nitric oxide (FeNO) level. Exercise intervention within 8 weeks only had a positive effect on forced vital capacity percentage (FVC%) and forced expiratory flow between 25% and 75% of forced vital capacity (FEF 25-75%) in children with asthma but had no positive effect on forced expiratory volume in 1 s percentage (FEV1%). Exercise intervention for more than 8 weeks had no positive effect on the above indicators. In children with asthma, exercise training has the potential to improve exercise ability and health quality of life but not inflammation. Additionally, exercise intervention does not provide sustained improvement of lung function, although training within 8 weeks can temporarily increase FVC% and FEF 25-75%.","PeriodicalId":55198,"journal":{"name":"Current Allergy and Asthma Reports","volume":"25 1","pages":"39"},"PeriodicalIF":4.6000,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Allergy and Asthma Reports","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s11882-025-01219-4","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ALLERGY","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose of review: Asthma is a heterogeneous respiratory condition and a common childhood disease. The effects of exercise on childhood asthma have not been fully clarified. This study aims to systematically evaluate the impact of exercise on children with asthma, specifically examining lung function, exercise capacity, airway inflammation, and health-related quality of life (HRQoL).

Recent findings: 13 randomized controlled trials (RCTs) involving 673 children with asthma, with a mean age ranging from 7.3 to 14 years, were included. The results of the meta-analysis showed that exercise can improve the six-minute walk test (6MWT) distance and the pediatric asthma quality of life questionnaire (PAQLQ) scores in children with asthma but cannot reduce the fractional exhaled nitric oxide (FeNO) level. Exercise intervention within 8 weeks only had a positive effect on forced vital capacity percentage (FVC%) and forced expiratory flow between 25% and 75% of forced vital capacity (FEF 25-75%) in children with asthma but had no positive effect on forced expiratory volume in 1 s percentage (FEV1%). Exercise intervention for more than 8 weeks had no positive effect on the above indicators. In children with asthma, exercise training has the potential to improve exercise ability and health quality of life but not inflammation. Additionally, exercise intervention does not provide sustained improvement of lung function, although training within 8 weeks can temporarily increase FVC% and FEF 25-75%.

查看原文本刊更多论文

运动对儿童哮喘的影响：随机对照试验的系统回顾和荟萃分析。

综述目的：哮喘是一种异质性呼吸系统疾病，是儿童常见病。运动对儿童哮喘的影响尚未完全阐明。本研究旨在系统评估运动对哮喘儿童的影响，特别是检查肺功能、运动能力、气道炎症和健康相关生活质量（HRQoL）。最近的发现：纳入了13项随机对照试验（RCTs），涉及673名哮喘儿童，平均年龄从7.3岁到14岁不等。meta分析结果显示，运动可提高哮喘患儿6分钟步行测试（6MWT）距离和儿童哮喘生活质量问卷（PAQLQ）得分，但不能降低呼气分数型一氧化氮（FeNO）水平。8周内运动干预仅对哮喘患儿用力肺活量百分比（FVC%）和用力肺活量25% ~ 75% （FEF 25 ~ 75%）的用力呼气流量有积极影响，而对用力呼气量百分比为1 s % （FEV1%）的用力呼气量无积极影响。运动干预超过8周对上述指标均无积极影响。对于患有哮喘的儿童，运动训练有可能改善运动能力和健康生活质量，但不能改善炎症。此外，运动干预不能提供持续的肺功能改善，尽管8周内的训练可以暂时增加FVC%和FEF 25-75%。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Current Allergy and Asthma Reports 医学-过敏

CiteScore

11.20

自引率

1.80%

发文量

审稿时长

6-12 weeks

期刊介绍： The aim of Current Allergy and Asthma Reports is to systematically provide the views of highly selected experts on current advances in the fields of allergy and asthma and highlight the most important papers recently published. All reviews are intended to facilitate the understanding of new advances in science for better diagnosis, treatment, and prevention of allergy and asthma. We accomplish this aim by appointing international experts in major subject areas across the discipline to review select topics emphasizing recent developments and highlighting important new papers and emerging concepts. We also provide commentaries from well-known figures in the field, and an Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research. Over a one- to two-year period, readers are updated on all the major advances in allergy and asthma.