MRI on a Budget: Leveraging Low and Ultra-Low Intensity Technology in Africa.

Khadija Khamis Ussi, Rovaldo Barbadis Mtenga
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Abstract

Magnetic resonance imaging (MRI) is a cornerstone of brain and spine diagnostics. Yet, access across Africa is limited by high installation costs, power requirements, and the need for specialized shielding and facilities. Low-and ultra low-field (ULF) MRI systems operating below 0.3 T are emerging as a practical alternative to expand neuroimaging capacity in resource-constrained settings. However, its faced with challenges that hinder its use in clinical setting. Technological advances that seek to tackle these challenges such as permanent Halbach array magnets, portable scanner designs such as those successfully deployed in Uganda and Malawi, and deep learning methods including convolutional neural network electromagnetic interference cancellation and residual U-Net image reconstruction have improved image quality and reduced noise, making ULF MRI increasingly viable. We review the state of low-field MRI technology, its application in point-of-care and rural contexts, and the specific limitations that remain, including reduced signal-to-noise ratio, larger voxel size requirements, and susceptibility to motion artifacts. Although not a replacement for high-field scanners in detecting subtle or small lesions, low-field MRI offers a promising pathway to broaden diagnostic imaging availability, support clinical decision-making, and advance equitable neuroimaging research in under-resourced regions.ABBREVIATIONS: CNN=Convolutional neural network; EMI=Electromagnetic interference; FID=Free induction wave; LMIC=Low and middle income countries; MRI=Magnetic Resonance Imaging; NCDs=Non communicable diseases; RF=Radiofrequency Pulse; SNR= Signal to noise ratio; TBI=Traumatic brain Injury.

预算核磁共振成像:利用低强度和超低强度技术在非洲。
磁共振成像(MRI)是脑和脊柱诊断的基石。然而,由于高昂的安装成本、电力需求以及对专门屏蔽和设施的需求,非洲各地的接入受到限制。工作强度低于0.3 T的低场和超低场(ULF) MRI系统正在成为在资源受限的环境中扩大神经成像能力的实用替代方案。然而,它面临着阻碍其在临床应用的挑战。解决这些挑战的技术进步,如永久性Halbach阵列磁体、便携式扫描仪设计(如在乌干达和马拉维成功部署的设计),以及包括卷积神经网络电磁干扰消除和残余U-Net图像重建在内的深度学习方法,提高了图像质量,降低了噪声,使ULF MRI越来越可行。我们回顾了低场MRI技术的现状,它在医疗点和农村环境中的应用,以及仍然存在的具体限制,包括降低信噪比,更大的体素尺寸要求,以及对运动伪影的敏感性。虽然在检测细微或小病变方面不能取代高场MRI,但低场MRI为扩大诊断成像的可用性、支持临床决策、促进资源不足地区公平的神经成像研究提供了一条有希望的途径。缩写:CNN=卷积神经网络;EMI =电磁干扰;FID=自由感应波;低收入和中等收入国家;磁共振成像;非传染性疾病;射频=射频脉冲;SNR=信噪比;TBI=创伤性脑损伤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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