Evaluation of Left Heart Function in Heart Failure Patients with Different Ejection Fraction Types using a Transthoracic Three-dimensional Echocardiography Heart-Model.

IF 1.1 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Shen-Yi Li, Yi Zhang, Qing-Qing Long, Ming-Juan Chen, Si-Yu Wang, Wei-Ying Sun
{"title":"Evaluation of Left Heart Function in Heart Failure Patients with Different Ejection Fraction Types using a Transthoracic Three-dimensional Echocardiography Heart-Model.","authors":"Shen-Yi Li, Yi Zhang, Qing-Qing Long, Ming-Juan Chen, Si-Yu Wang, Wei-Ying Sun","doi":"10.2174/0115734056388350250903130655","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Heart failure (HF) is classified into three types based on left ventricular ejection fraction (LVEF). A newly developed transthoracic threedimensional (3D) echocardiography Heart-Model (HM) offers quick analysis of the volume and function of the left atrium (LA) and left ventricle (LV). This study aimed to determine the value of the HM in HF patients.</p><p><strong>Methods: </strong>A total of 117 patients with HF were divided into three groups according to EF: preserved EF (HFpEF, EF ≥50%), mid-range EF (HFmrEF, EF =41%-49%), and reduced EF (HFrEF, EF ≤40%). The HM was applied to analyze 3D cardiac functional parameters. LVEF was obtained using Simpson's biplane method. The N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentration was measured.</p><p><strong>Results: </strong>Significant differences in age, female proportion, body mass index, and comorbidities were observed among the three groups. With decreasing EF across the groups, the 3D volumetric parameters of the LA and LV increased, while LVEF decreased. The LV E/e' was significantly higher in HFrEF patients than in HFpEF patients. LVEF measurement was achieved in significantly less time with the HM compared with the conventional Simpson's biplane method. The NT-proBNP concentration increased in the following pattern: HFrEF > HFmrEF > HFpEF. The NT-proBNP concentration correlated positively with LV volume and negatively with LVEF from both the HM and Simpson's biplane method.</p><p><strong>Conclusion: </strong>LA and LV volumes increase, and the derived LV systolic function decreases with increasing HF severity determined by the HM. The functional parameters measurements provided by the HM are associated with laboratory indicators, indicating the feasibility of using the HM in routine clinical application.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1000,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Medical Imaging Reviews","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2174/0115734056388350250903130655","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0

Abstract

Objective: Heart failure (HF) is classified into three types based on left ventricular ejection fraction (LVEF). A newly developed transthoracic threedimensional (3D) echocardiography Heart-Model (HM) offers quick analysis of the volume and function of the left atrium (LA) and left ventricle (LV). This study aimed to determine the value of the HM in HF patients.

Methods: A total of 117 patients with HF were divided into three groups according to EF: preserved EF (HFpEF, EF ≥50%), mid-range EF (HFmrEF, EF =41%-49%), and reduced EF (HFrEF, EF ≤40%). The HM was applied to analyze 3D cardiac functional parameters. LVEF was obtained using Simpson's biplane method. The N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentration was measured.

Results: Significant differences in age, female proportion, body mass index, and comorbidities were observed among the three groups. With decreasing EF across the groups, the 3D volumetric parameters of the LA and LV increased, while LVEF decreased. The LV E/e' was significantly higher in HFrEF patients than in HFpEF patients. LVEF measurement was achieved in significantly less time with the HM compared with the conventional Simpson's biplane method. The NT-proBNP concentration increased in the following pattern: HFrEF > HFmrEF > HFpEF. The NT-proBNP concentration correlated positively with LV volume and negatively with LVEF from both the HM and Simpson's biplane method.

Conclusion: LA and LV volumes increase, and the derived LV systolic function decreases with increasing HF severity determined by the HM. The functional parameters measurements provided by the HM are associated with laboratory indicators, indicating the feasibility of using the HM in routine clinical application.

应用经胸三维超声心动图心脏模型评价不同射血分数类型心衰患者左心功能。
目的:根据左心室射血分数(LVEF)将心力衰竭分为三种类型。一种新开发的经胸三维超声心动图心脏模型(HM)可以快速分析左心房(LA)和左心室(LV)的体积和功能。本研究旨在确定HM在HF患者中的价值。方法:117例心衰患者根据EF分为保存型EF (HFpEF, EF≥50%)、中程型EF (HFmrEF, EF =41% ~ 49%)、减少型EF (HFrEF, EF≤40%)3组。应用HM分析三维心功能参数。LVEF采用Simpson双翼法计算。测定n端前b型利钠肽(NT-proBNP)浓度。结果:三组患者在年龄、女性比例、体重指数、合并症等方面均存在显著差异。随着各实验组EF的减小,左室和左室三维体积参数增大,LVEF减小。HFrEF患者的LV E/ E′明显高于HFpEF患者。与传统的Simpson双翼方法相比,HM测量LVEF的时间明显更短。NT-proBNP浓度增加规律如下:HFrEF > HFmrEF > HFpEF。HM和Simpson双平面法测得NT-proBNP浓度与左室容积呈正相关,与LVEF呈负相关。结论:随着HM测定的HF严重程度的增加,左室和左室容积增加,左室收缩功能下降。HM提供的功能参数测量与实验室指标相关联,表明HM在常规临床应用中的可行性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
2.60
自引率
0.00%
发文量
246
审稿时长
1 months
期刊介绍: Current Medical Imaging Reviews publishes frontier review articles, original research articles, drug clinical trial studies and guest edited thematic issues on all the latest advances on medical imaging dedicated to clinical research. All relevant areas are covered by the journal, including advances in the diagnosis, instrumentation and therapeutic applications related to all modern medical imaging techniques. The journal is essential reading for all clinicians and researchers involved in medical imaging and diagnosis.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信