Epidemiological analysis and detection of a 27a-like porcine parvovirus strain with pathogenicity in pregnant sows in Japan.

IF 1.1 4区农林科学 Q3 VETERINARY SCIENCES

Journal of Veterinary Medical Science Pub Date : 2025-09-18 DOI:10.1292/jvms.25-0291

Tetsuo Sato, Shizuka Hayashi, Katsuaki Sugiura

引用次数: 0

Abstract

Porcine parvovirus (PPV) is a major cause of reproductive failure in pigs. This study reports the first detection of a PPV 27a-like strain in Japan. A total of 387 samples from 113 cases (2015-2024) were analyzed, revealing 35 PPV-positive cases. Phylogenetic analysis identified the NG2794-2-3/2019 strain as a 27a-like variant. Experimental infection in pregnant sows resulted in fetal death and mummification, confirming pathogenicity. The strain exhibited prolonged viremia, indicating a high transmission risk. Owing to antigenic differences from vaccine strains, conventional PPV vaccines may be ineffective. This study highlights the urgent need for enhanced vaccines to control PPV-related reproductive disorders in Japan.

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日本一株具有致病性的27a样猪细小病毒株的流行病学分析与检测。

猪细小病毒（PPV）是猪繁殖失败的主要原因。这项研究报告了日本首次检测到PPV 27a样菌株。共分析113例（2015-2024年）387份样本，其中ppv阳性35例。系统发育分析确定NG2794-2-3/2019菌株为27a样变体。实验感染妊娠母猪导致胎儿死亡和木乃伊化，证实致病性。该毒株表现出长时间的病毒血症，表明具有很高的传播风险。由于疫苗株的抗原差异，传统的PPV疫苗可能无效。这项研究强调了在日本迫切需要加强疫苗来控制ppv相关的生殖疾病。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Veterinary Medical Science 农林科学-兽医学

CiteScore

2.30

自引率

8.30%

发文量

230

审稿时长

9-18 weeks

期刊介绍： JVMS is a peer-reviewed journal and publishes a variety of papers on veterinary science from basic research to applied science and clinical research. JVMS is published monthly and consists of twelve issues per year. Papers are from the areas of anatomy, physiology, pharmacology, toxicology, pathology, immunology, microbiology, virology, parasitology, internal medicine, surgery, clinical pathology, theriogenology, avian disease, public health, ethology, and laboratory animal science. Although JVMS has played a role in publishing the scientific achievements of Japanese researchers and clinicians for many years, it now also accepts papers submitted from all over the world.