The effect of intensity on metabolic and ventilatory responses to steady-state exercise in women across the adult lifecycle.

IF 2.7 3区医学 Q2 PHYSIOLOGY

European Journal of Applied Physiology Pub Date : 2025-09-19 DOI:10.1007/s00421-025-05981-1

Catherine A Rattley, Paul Ansdell, Matthew Armstrong, Malika Felton, Susan Dewhurst, Karen Yendole, Rebecca A Neal

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引用次数: 0

Abstract

Aim: This study aimed to investigate the differences in metabolism and ventilation between women before, during, and after menopause during rest and to varying steady-state exercise intensities.

Method: 74 female participants (18-60 years; premenopausal [PRE], perimenopausal [PERI], and postmenopausal [POST]) completed four laboratory visits; one maximal exercise test, resting data collection, and body composition assessment followed by three steady-state submaximal exercise tests at 40% (low), 60% (moderate), and 80% (high) V̇O_2peak in a randomised order with subgroup analysis for hormonal contraceptive or hormone therapy use.

Results: There was an effect of menopause stage on exercise energy expenditure but no interaction effect with intensity. There were no differences substrate utilisation, or ventilation across any of the exercise intensities. Subgroup analysis revealed that HT and HC use did not impact EE, substrate oxidation, or ventilation.

Conclusions: Menopause stage is influential upon exercise energy expenditure but more research in perimenopause is required to confirm the effect, future studies should explore the broader implications of the menopausal transition on exercise physiology.

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强度对成年女性稳态运动代谢和通气反应的影响。

目的：本研究旨在探讨绝经前、绝经中、绝经后女性在休息和不同的稳态运动强度时代谢和通气的差异。方法：74名女性参与者（18-60岁，绝经前[PRE]，围绝经期[PERI]和绝经后[POST]）完成4次实验室检查；1次最大运动试验、静息数据收集和体成分评估，随后进行3次稳态次最大运动试验，分别为40%（低）、60%（中等）和80%（高）V / o峰值，随机顺序进行，并对激素避孕或激素治疗使用进行亚组分析。结果：绝经期对运动能量消耗有影响，但与运动强度无交互作用。在任何运动强度下，基质利用率或通风都没有差异。亚组分析显示，HT和HC的使用对EE、底物氧化或通气没有影响。结论：绝经期对运动能量消耗有影响，但需要更多的围绝经期研究来证实这种影响，未来的研究应探讨绝经期过渡对运动生理学的更广泛影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Journal of Applied Physiology 医学-生理学

CiteScore

6.00

自引率

6.70%

发文量

227

审稿时长

3 months

期刊介绍： The European Journal of Applied Physiology (EJAP) aims to promote mechanistic advances in human integrative and translational physiology. Physiology is viewed broadly, having overlapping context with related disciplines such as biomechanics, biochemistry, endocrinology, ergonomics, immunology, motor control, and nutrition. EJAP welcomes studies dealing with physical exercise, training and performance. Studies addressing physiological mechanisms are preferred over descriptive studies. Papers dealing with animal models or pathophysiological conditions are not excluded from consideration, but must be clearly relevant to human physiology.