Targeting the Secretin Receptor in Macrophages Attenuates Silica-Induced Pulmonary Fibrosis.

IF 5.6 1区生物学 Q2 CELL BIOLOGY

Cell Proliferation Pub Date : 2025-09-18 DOI:10.1111/cpr.70131

Yaqian Li, Tian Li, Fuyu Jin, Shupeng Liu, Dingjie Xu, Zhongqiu Wei, Xuemin Gao, Wenchen Cai, Na Mao, Fang Yang, Haibo Zhang, Yiwei Shi, Hong Xu

引用次数: 0

Abstract

Targeting macrophage SCTR mitigates integrated profibrotic, inflammatory, ER stress, and senescent pathways, preserving lung function and revealing a novel therapeutic strategy for silicosis.

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靶向巨噬细胞分泌素受体减轻二氧化硅诱导的肺纤维化。

靶向巨噬细胞SCTR减轻综合纤维化、炎症、内质网应激和衰老途径，保护肺功能，揭示一种新的矽肺治疗策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cell Proliferation 生物-细胞生物学

CiteScore

14.80

自引率

2.40%

发文量

198

审稿时长

1 months

期刊介绍： Cell Proliferation Focus: Devoted to studies into all aspects of cell proliferation and differentiation. Covers normal and abnormal states. Explores control systems and mechanisms at various levels: inter- and intracellular, molecular, and genetic. Investigates modification by and interactions with chemical and physical agents. Includes mathematical modeling and the development of new techniques. Publication Content: Original research papers Invited review articles Book reviews Letters commenting on previously published papers and/or topics of general interest By organizing the information in this manner, readers can quickly grasp the scope, focus, and publication content of Cell Proliferation.