Prevalence of Trypanosoma cruzi Antibodies in Wild Pigs (Sus scrofa) in the USA.

IF 1.2 4区农林科学 Q3 VETERINARY SCIENCES

Journal of Wildlife Diseases Pub Date : 2025-09-18 DOI:10.7589/JWD-D-25-00020

Taylor A Fisher, Sarah M Coker, Raquel Francisco, Bailey Ward, Vienna R Brown, Michael J Yabsley, Ellen Haynes, Christopher A Cleveland

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引用次数: 0

Abstract

Wild pig (Sus scrofa) populations are expanding across the US, raising concerns about the ecologic impacts and role as reservoirs for pathogens of significance to human and animal health. Trypanosoma cruzi, the causative agent of Chagas disease, is a recognized risk for humans and domestic dogs in the southern US. Common wildlife reservoirs of T. cruzi include rodents (e.g., Neotoma spp.), raccoons (Procyon lotor), and Virginia opossums (Didelphus virginiana); however, there have been reports of T. cruzi infection in suids, including a domestic pig (Sus scrofa domesticus) in Mexico and three wild pigs in Texas, US. Our study aimed to better understand the prevalence and distribution of T. cruzi antibodies in wild pigs in the US. We collected 1,093 serum samples from wild pigs across 12 states in the southern, midwestern, and western regions of the US, all of which have populations of T. cruzi triatomine vectors. We tested sera for antibodies against T. cruzi using an indirect ELISA and detected an overall apparent prevalence of 14.6% (160/1,093; 95% confidence interval, 12.6-16.9%). Pig sex, age class, month of sampling, and region were not significantly associated with seroprevalence; however, state of origin explained some variation in the data. We demonstrated that wild pigs in the US were exposed to T. cruzi, highlighting the need for further research elucidating their role in T. cruzi transmission.

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美国野猪（Sus scrofa）克氏锥虫抗体的流行情况。

野猪（Sus scrofa）种群在美国各地不断扩大，引起了人们对生态影响和对人类和动物健康具有重要意义的病原体宿主作用的担忧。克氏锥虫是恰加斯病的病原体，是美国南部人类和家养狗的公认风险。克氏弓形虫的常见野生宿主包括啮齿动物（如Neotoma spp.）、浣熊（Procyon lotor）和弗吉尼亚负鼠（Didelphus Virginia）；然而，有猪感染克氏t型病毒的报告，包括墨西哥的一头家猪和美国德克萨斯州的三只野猪。本研究旨在更好地了解克氏t型病毒抗体在美国野猪中的流行和分布情况。我们从美国南部、中西部和西部地区的12个州的野猪中收集了1093份血清样本，这些州都有克氏锥虫病媒。我们使用间接ELISA检测血清抗克氏t型虫抗体，检测到总体表观患病率为14.6%（160/ 1093；95%可信区间为12.6-16.9%）。猪的性别、年龄、取样月份和地区与血清阳性率无显著相关；然而，原始状态解释了数据中的一些变化。我们证明了美国的野猪暴露于克氏t型病毒，强调需要进一步研究阐明它们在克氏t型病毒传播中的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Wildlife Diseases 农林科学-兽医学

CiteScore

2.70

自引率

0.00%

发文量

213

审稿时长

6-16 weeks

期刊介绍： The JWD publishes reports of wildlife disease investigations, research papers, brief research notes, case and epizootic reports, review articles, and book reviews. The JWD publishes the results of original research and observations dealing with all aspects of infectious, parasitic, toxic, nutritional, physiologic, developmental and neoplastic diseases, environmental contamination, and other factors impinging on the health and survival of free-living or occasionally captive populations of wild animals, including fish, amphibians, reptiles, birds, and mammals. Papers on zoonoses involving wildlife and on chemical immobilization of wild animals are also published. Manuscripts dealing with surveys and case reports may be published in the Journal provided that they contain significant new information or have significance for better understanding health and disease in wild populations. Authors are encouraged to address the wildlife management implications of their studies, where appropriate.