{"title":"Perfluorodecalin Toxicity Following Retinal Autograft Surgery in a Case With Chronic Recurrent Large Macular Hole.","authors":"Semra Tiryaki Demir, Merve Hotoglu","doi":"10.3928/23258160-20250805-04","DOIUrl":null,"url":null,"abstract":"<p><p>In cases with chronic recurrent large macular holes (MH), retinal autograft can be used to close the MH and perfluorocarbon liquids can be left in the eye for a short time to stabilize the graft. However, there are some cases reported in the literature regarding retinal toxicity due to the use of perfluorocarbon liquids as tamponade in vitreo-retinal surgery. This case report presents a 49-year-old patient with chronic recurrent large MH despite undergoing vitrectomy and internal limiting membrane peeling surgery 8 years prior. Retinal autograft was used to close the MH and stabilization of the autograft was achieved with short-term perfluorodecalin liquid tamponade. However, after the removal of perfluorodecalin fluid, widespread retinal toxicity developed in the macula.</p>","PeriodicalId":19679,"journal":{"name":"Ophthalmic surgery, lasers & imaging retina","volume":" ","pages":"1-3"},"PeriodicalIF":1.1000,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ophthalmic surgery, lasers & imaging retina","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3928/23258160-20250805-04","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
In cases with chronic recurrent large macular holes (MH), retinal autograft can be used to close the MH and perfluorocarbon liquids can be left in the eye for a short time to stabilize the graft. However, there are some cases reported in the literature regarding retinal toxicity due to the use of perfluorocarbon liquids as tamponade in vitreo-retinal surgery. This case report presents a 49-year-old patient with chronic recurrent large MH despite undergoing vitrectomy and internal limiting membrane peeling surgery 8 years prior. Retinal autograft was used to close the MH and stabilization of the autograft was achieved with short-term perfluorodecalin liquid tamponade. However, after the removal of perfluorodecalin fluid, widespread retinal toxicity developed in the macula.
期刊介绍：
OSLI Retina focuses exclusively on retinal diseases, surgery and pharmacotherapy. OSLI Retina will offer an expedited submission to publication effort of peer-reviewed clinical science and case report articles. The front of the journal offers practical clinical and practice management features and columns specific to retina specialists. In sum, readers will find important peer-reviewed retina articles and the latest findings in techniques and science, as well as informative business and practice management features in one journal.
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