RETRACTION: Evidence That Low Doses of Taxol Enhance the Functional Transactivatory Properties of p53 on p21 Waf Promoter in MCF-7 Breast Cancer Cells.
IF 3 4区 生物学Q1 Biochemistry, Genetics and Molecular Biology
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引用次数: 0
Abstract
Retraction: M. L. Panno , F. Giordano , F. Mastroianni , C. Morelli , E. Brunelli , M. G. Palma , M. Pellegrino , S. Aquila , A. Miglietta , L. Mauro , D. Bonofiglio , and S. Andò , "Evidence That Low Doses of Taxol Enhance the Functional Transactivatory Properties of p53 on p21 Waf Promoter in MCF-7 Breast Cancer Cells," FEBS Letters 580, no. 9 (2006): 2371-2380, https://doi.org/10.1016/j.febslet.2006.03.055. The above article, published online on 29 March 2006 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief, Michael Brunner; FEBS Press; and John Wiley and Sons Ltd. The retraction has been agreed upon following an investigation prompted by concerns raised by a third party. The investigation identified inappropriate duplications of image sections in Figures 4, 5, and 10. The authors' explanation was found to be insufficient to resolve these concerns, and due to the time elapsed since the original publication, the raw data could no longer be retrieved. However, the extent and nature of the inconsistencies identified in the published figures raised significant concerns regarding the data. As a result, the editors no longer have confidence in the integrity of the presented data and consider the study's conclusions to be compromised. The authors do not agree with this retraction.
撤回:M. L. Panno, F. Giordano, F. Mastroianni, C. Morelli, E. Brunelli, M. G. Palma, M. Pellegrino, S. Aquila, A. Miglietta, L. Mauro, D. Bonofiglio, S. Andò,“低剂量紫杉醇增强MCF-7乳腺癌细胞中p21 Waf启动子p53的功能转激活特性的证据”,《中华医学杂志》,第580期。9 (2006): 2371-2380, https://doi.org/10.1016/j.febslet.2006.03.055。上述文章于2006年3月29日发表在Wiley在线图书馆(wileyonlinelibrary.com)上,经该杂志总编辑迈克尔·布伦纳(Michael Brunner)同意撤回;2月出版社;及约翰威利父子有限公司。在第三方提出的担忧引发调查后,双方同意撤回这篇文章。调查发现了图4、5和10中图像部分的不适当重复。作者的解释被认为不足以解决这些问题,并且由于原始出版物已经过了一段时间,原始数据已无法检索。然而,在公布的数字中发现的不一致的程度和性质引起了人们对数据的重大关切。因此,编辑们对所提交数据的完整性不再有信心,并认为研究的结论受到了损害。作者不同意这次撤稿。
期刊介绍:
FEBS Letters is one of the world''s leading journals in molecular biology and is renowned both for its quality of content and speed of production. Bringing together the most important developments in the molecular biosciences, FEBS Letters provides an international forum for Minireviews, Research Letters and Hypotheses that merit urgent publication.