Presentation of Extended-Spectrum Beta-Lactamase-Producing Escherichia Coli Sequence Type 58 Strain (ST58) with Solid Subcutaneous Mass and Hypermucoid Phenotype: A Case Report.

IF 1 4区 医学 Q4 MEDICAL LABORATORY TECHNOLOGY
Miguel Carabaño, Eunji Jang, Swapna Charla, Gerard Nau, Sara Geffert, Ece D Gamsiz Uzun, Tao Hong
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引用次数: 0

Abstract

Escherichia coli (E. coli) is a versatile bacterium, presenting a wide variety of virulence factors contributing to intestinal and extraintestinal disease. This paper presents a unique case of Escherichia coli strain exhibiting an extended-spectrum beta-lactamase (ESBL) as determined by minimum inhibitory concentration (MIC), identified as sequence type 58 (ST58). The strain, isolated from a clinical specimen, displayed unusual characteristics, forming a solid subcutaneous mass and presenting a hypermucoid phenotype. Comprehensive analysis, including whole-genome sequencing (WGS) and conventional serotyping, was conducted to understand the genetic and phenotypic features of this atypical E. coli strain.

广谱产β -内酰胺酶大肠杆菌序列58型菌株(ST58)具有固体皮下肿块和高黏液样表型:1例报告。
大肠杆菌(E. coli)是一种多用途细菌,呈现出多种导致肠道和肠外疾病的毒力因子。本文报道了一株具有广谱β -内酰胺酶(ESBL)的独特大肠杆菌菌株,经最小抑制浓度(MIC)测定,鉴定为序列型58 (ST58)。从临床标本中分离出的菌株表现出不寻常的特征,形成固体皮下肿块并呈现超粘液样表型。通过全基因组测序(WGS)和常规血清分型等综合分析,了解该非典型大肠杆菌的遗传和表型特征。
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来源期刊
Annals of clinical and laboratory science
Annals of clinical and laboratory science 医学-医学实验技术
CiteScore
1.60
自引率
0.00%
发文量
112
审稿时长
6-12 weeks
期刊介绍: The Annals of Clinical & Laboratory Science welcomes manuscripts that report research in clinical science, including pathology, clinical chemistry, biotechnology, molecular biology, cytogenetics, microbiology, immunology, hematology, transfusion medicine, organ and tissue transplantation, therapeutics, toxicology, and clinical informatics.
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