{"title":"Development of a Fully Paper-Based Device for Quantitative Detection of Digoxin at the Point of Care","authors":"Kyle Chen, Jiakun Lu, Jasmine Thanh Trinh, Audrey Theresa Sogata, Rika Nicole Lumagbas Canlas, Daniel Kamei","doi":"10.1039/d5an00800j","DOIUrl":null,"url":null,"abstract":"We are the first to integrate H<small><sub>2</sub></small>O<small><sub>2</sub></small> degradation and gold nanorod (GNR) etching on paper with the lateral-flow immunoassay (LFA) in a 3D-printed device to achieve semi-quantitative results for therapeutic drug monitoring of digoxin by correlating different color outputs to different digoxin concentrations.","PeriodicalId":63,"journal":{"name":"Analyst","volume":"105 1","pages":""},"PeriodicalIF":3.3000,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Analyst","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1039/d5an00800j","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
Abstract
We are the first to integrate H2O2 degradation and gold nanorod (GNR) etching on paper with the lateral-flow immunoassay (LFA) in a 3D-printed device to achieve semi-quantitative results for therapeutic drug monitoring of digoxin by correlating different color outputs to different digoxin concentrations.