Evaluation of the Relationship Between Prognostic Nutritional Index and Early Clinical Outcomes in Intestinal Transplantation.

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Transplantation proceedings Pub Date : 2025-09-15 DOI:10.1016/j.transproceed.2025.09.002

Göksever Akpınar, Batuhan Eyduran, Safa Vatansever, Ekrem Kocatürk, Mehmet Üstün

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Abstract

Background: Malnutrition in patients with intestinal insufficiency negatively affects the success of intestinal transplantation. In our research, we assessed patients' nutritional status using the PNI scale and examined the impact of the PNI score on clinical outcomes during the post-transplant phase.

Results: The acute rejection rate was 38.1%, and the 30-day survival rate was 90.5%. Median PNI values were 41.5 (min-max: 33.5-65), 29.5 (min-max: 13.5-56.5), 33 (min-max: 3-51), 35.7 (min-max: 24.5-54), 33.5 (min-max: 24.5-75.5) preoperatively and on postoperative 1, 7, 15, and 30 days, respectively. No significant relationship was found between the other parameters and the PNI.

Conclusions: The PNI score alone fails to adequately represent a patient's nutritional status and has not demonstrated effectiveness in predicting early-term outcomes for those undergoing intestinal transplantation. Additional studies involving a larger number of patients and diverse nutritional markers are necessary for further insights into this matter.

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肠移植患者预后营养指数与早期临床结果的关系评价。

背景：肠功能不全患者的营养不良会对肠移植的成功产生负面影响。在我们的研究中，我们使用PNI量表评估患者的营养状况，并检查PNI评分对移植后临床结果的影响。结果：急性排斥反应率为38.1%，30天生存率为90.5%。术前、术后1、7、15、30天PNI中位值分别为41.5 （min-max: 33.5-65）、29.5 （min-max: 13.5-56.5）、33 （min-max: 3-51）、35.7 （min-max: 24.5-54）、33.5 （min-max: 24.5-75.5）。其他参数与PNI无显著关系。结论：单独的PNI评分不能充分代表患者的营养状况，也不能有效预测肠移植患者的早期预后。为了进一步了解这一问题，有必要进行涉及更多患者和不同营养指标的额外研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Transplantation proceedings

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