Yossawee Wongworawut, Peter H Hwang, Jayakar V Nayak, Robert Dodd, Juan C Fernandez-Miranda, Zara M Patel
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引用次数: 0
Abstract
Objectives: Local effects of pituitary hormones in the sinonasal region are not well characterized. We sought to examine sinonasal quality of life outcomes in functional and non-functional pituitary tumors after endoscopic skull base surgery.
Study design: Retrospective Medical Record Review.
Methods: Three hundred four patients who received endoscopic resection of a pituitary tumor at a tertiary skull base center reviewed. This population was divided into non-functional and functional groups. Surgical outcomes and pre and postoperative quality of life scores were examined.
Results: Preoperative total SNOT 22 scores were not different overall between the two groups, but the rhinologic and extra-nasal rhinologic subdomain scores in the functional group were higher than in the non-functional group (3.57 ± 3.95 vs. 2.58 ± 3.64, and 1.48 ± 2.2 vs. 0.92 ± 1.75 respectively) (p = 0.04 and 0.02). Change from baseline in overall postoperative SNOT 22 score was significantly greater in the functional group at 6 weeks post-operation (6.75 ± 17.51 vs. 1.4 ± 16.83 respectively) (p = 0.03). Time to normalization on nasal endoscopy was longer in the functional group compared to the non-functional group (p = 0.02).
Conclusion: Corticotrophic and somatotrophic tumors affect quality of life both pre- and post-operation. Patients with functional tumors took longer to reach full healing and normalization of the sinus cavity. These findings can be used to counsel patients about different expectations during the immediate postoperative healing period, but also to reassure them that regardless of tumor functionality, they will be able to reach a good quality of life after endoscopic skull base surgery.
期刊介绍：
The Laryngoscope has been the leading source of information on advances in the diagnosis and treatment of head and neck disorders since 1890. The Laryngoscope is the first choice among otolaryngologists for publication of their important findings and techniques. Each monthly issue of The Laryngoscope features peer-reviewed medical, clinical, and research contributions in general otolaryngology, allergy/rhinology, otology/neurotology, laryngology/bronchoesophagology, head and neck surgery, sleep medicine, pediatric otolaryngology, facial plastics and reconstructive surgery, oncology, and communicative disorders. Contributions include papers and posters presented at the Annual and Section Meetings of the Triological Society, as well as independent papers, "How I Do It", "Triological Best Practice" articles, and contemporary reviews. Theses authored by the Triological Society’s new Fellows as well as papers presented at meetings of the American Laryngological Association are published in The Laryngoscope.
• Broncho-esophagology
• Communicative disorders
• Head and neck surgery
• Plastic and reconstructive facial surgery
• Oncology
• Speech and hearing defects
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