Short-Term Effects of Platelet-Rich Plasma on the Clinical Outcomes of Dental Autotransplantation in Teeth with Complete and Incomplete Root Development: A Randomized Cohort Study.
Aysenur Genc, Betul Gedik, Mehmet Ali Erdem, Abdulkadir Burak Cankaya
{"title":"Short-Term Effects of Platelet-Rich Plasma on the Clinical Outcomes of Dental Autotransplantation in Teeth with Complete and Incomplete Root Development: A Randomized Cohort Study.","authors":"Aysenur Genc, Betul Gedik, Mehmet Ali Erdem, Abdulkadir Burak Cankaya","doi":"10.7150/ijms.113282","DOIUrl":null,"url":null,"abstract":"<p><p><b>Background:</b> Dental autotransplantation, the surgical relocation of a tooth within the same individual, offers a valuable alternative to implants for preserving alveolar bone integrity and achieving functional restoration. This study aimed to assess the short-term impact of platelet-rich plasma (PRP) on clinical outcomes in autotransplanted teeth with fully and partially developed roots. <b>Methods:</b> A total of 20 patients, aged 18-25, were randomly assigned to either a PRP or non-PRP group, with subgroups based on root development stage. Key outcomes-including tooth vitality, periodontal probing depth, mobility, pain, and root resorption-were evaluated at 1 week, 1, 3, 6, and 12 months post-transplant. <b>Results:</b> Findings indicated no statistically significant differences between PRP-treated and control groups across all outcomes, suggesting limited PRP efficacy in enhancing short-term outcomes in mature teeth with developed roots. <b>Conclusions:</b> These results underscore the importance of root maturity and atraumatic surgical technique in autotransplantation success, while highlighting that PRP may not significantly affect outcomes in teeth with completed root development.</p>","PeriodicalId":14031,"journal":{"name":"International Journal of Medical Sciences","volume":"22 14","pages":"3617-3624"},"PeriodicalIF":3.2000,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12434814/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Medical Sciences","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.7150/ijms.113282","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Dental autotransplantation, the surgical relocation of a tooth within the same individual, offers a valuable alternative to implants for preserving alveolar bone integrity and achieving functional restoration. This study aimed to assess the short-term impact of platelet-rich plasma (PRP) on clinical outcomes in autotransplanted teeth with fully and partially developed roots. Methods: A total of 20 patients, aged 18-25, were randomly assigned to either a PRP or non-PRP group, with subgroups based on root development stage. Key outcomes-including tooth vitality, periodontal probing depth, mobility, pain, and root resorption-were evaluated at 1 week, 1, 3, 6, and 12 months post-transplant. Results: Findings indicated no statistically significant differences between PRP-treated and control groups across all outcomes, suggesting limited PRP efficacy in enhancing short-term outcomes in mature teeth with developed roots. Conclusions: These results underscore the importance of root maturity and atraumatic surgical technique in autotransplantation success, while highlighting that PRP may not significantly affect outcomes in teeth with completed root development.
期刊介绍:
Original research papers, reviews, and short research communications in any medical related area can be submitted to the Journal on the understanding that the work has not been published previously in whole or part and is not under consideration for publication elsewhere. Manuscripts in basic science and clinical medicine are both considered. There is no restriction on the length of research papers and reviews, although authors are encouraged to be concise. Short research communication is limited to be under 2500 words.