Biological effects of epoxy resins on the human body: toxicity and allergic reactions.

Abstract

This research focused on assessing the impact of epoxy resin components on human health and formulating measures to mitigate their adverse effects. The investigation highlighted the primary routes of exposure to toxic substances, including the inhalation of volatile compounds and direct contact with skin or mucous membranes. The most hazardous components were identified as epichlorohydrin, bisphenol A, and amine hardeners, which were associated with both immediate and long-term toxic effects, such as irritation, inflammatory responses, and the potential for tissue accumulation. Particular attention was directed to sensitization processes resulting from the interaction of epoxy resin constituents with proteins in the skin or mucous membranes, leading to allergic responses like contact dermatitis and systemic sensitization. Additionally, the study examined the influence of occupational settings on the toxicity of these substances, with a focus on measuring the levels of volatile organic compounds present in workplace environments. The study integrated a comprehensive review of scientific literature, experimental findings, and an assessment of toxicity, with a particular focus on industrial applications. Based on the findings, practical recommendations were proposed, including the implementation of personal protective equipment, the automation of production processes, the substitution of hazardous components with safer alternatives, and the establishment of monitoring systems to safeguard worker health. These outcomes are applicable in the manufacturing and utilization of epoxy resins, aiming to mitigate health hazards and enhance environmental sustainability.