[Application of Forensic Transcriptomics in the Identification of Tissue Origin of Body Fluid Stains].

Abstract

The inference of tissue origin of body fluid stains is crucial for case investigation and court proceedings. However, traditional methods for identification of body fluid stains, such as morphological, chemical, and immunoassay identifications have certain limitations, and there is an urgent need for more efficient methods for confirmatory experiments. In recent years, the rapid development of transcriptomics technology has provided new means for the identification of tissue origin of body fluid stains. Different types of RNA in the transcriptome have their own advantages. This paper elaborates in detail on the application of different types of RNA, such as mRNA, miRNA, circRNA, lncRNA, piRNA and microbial transcriptomics in body fluid identification, and summarizes their respective advantages and limitations, in order to provide a reference for related research.