Predictors of ST-Segment Resolution and Its Relationship With Outcomes in Patients With ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention.
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引用次数: 0
Abstract
ST-segment resolution (STR) is a critical parameter in ST-elevation myocardial infarction (STEMI) patients treated with primary percutaneous coronary intervention (pPCI). This study aimed to determine predictors of incomplete STR and their relationship with adverse cardiovascular outcomes. The study retrospectively included 508 consecutive STEMI patients who underwent pPCI in our hospital between January 2020 and December 2020. Patients with STR < 70% were included in the incomplete STR group (n = 182), and patients with STR ≥ 70% were included in the complete STR group (n = 326). Multivariable analysis identified in-stent restenosis (Odds ratio [OR] = 5.145), prolonged ischemic time (OR = 1.100), and left ventricular ejection fraction (LVEF; OR = 0.968) as independent predictors. Receiver operating curve (ROC) analysis found 4.5 hours of ischemic time and 49% LVEF as cutoff values. Kaplan-Meier analyses showed that incomplete STR correlated with greater 1- and 5-year mortality. In our study, the independent predictors of incomplete STR were LVEF, in-stent restenosis, and total ischemic time. In addition, incomplete STR was associated with in-stent restenosis, in-hospital, 1-year, and 5-year all-cause mortality. Our findings may prove useful in managing STEMI patients.
期刊介绍:
A presentation of original, peer-reviewed original articles, review and case reports relative to all phases of all vascular diseases, Angiology (ANG) offers more than a typical cardiology journal. With approximately 1000 pages per year covering diagnostic methods, therapeutic approaches, and clinical and laboratory research, ANG is among the most informative publications in the field of peripheral vascular and cardiovascular diseases. This journal is a member of the Committee on Publication Ethics (COPE). Average time from submission to first decision: 13 days