Excision of extensive subretinal fibrosis associated with rhegmatogenous retinal detachments in patients with familial exudative vitreoretinopathy.

IF 2.1 2区医学 Q2 OPHTHALMOLOGY

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-09-10 DOI:10.1097/IAE.0000000000004686

Hiroyuki Kondo, Itsuka Matsushita, Mizuki Tsurusaki

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引用次数: 0

Abstract

Purpose: To determine the characteristics and treatment of the extensive subretinal fibrosis (ESF) in eyes with rhegmatogenous retinal detachment (RRD) but without a tractional retinal detachment in patients with familial exudative vitreoretinopathy (FEVR).

Methods: Ten eyes of 9 men and 1 woman with ESF in patients with RRD-FEVR were studied. The characteristics, surgical procedures, and the outcomes after the removal of the ESF were determined. The ESF was excised by either stripping the ESF from small retinotomies or by en bloc excision through a >180° retinotomy or retinectomy at the ora serrata.

Results: The median age of the patients was 12.5-years. All cases had a unilateral macula-off retinal detachment with a total detachment in 4 eyes and detachment over 2 quadrants in 6 eyes. The first case underwent ESF stripping through small retinotomies that required 7 additional surgeries with a final visual acuity (VA) of hand motion. The subsequent 9 cases underwent en bloc excision resulting in a retinal reattachment with silicone oil tamponade. The silicone oil was removed without a recurrence of the RD during a median follow-up period of 7 years. The median final VA was 20/66 with a range of 20/17 to 20/500.

Conclusion: ESF can be found in FEVR eyes with a slowly progressive RRD. We conclude that the en bloc excision of the ESF is an effective and safe procedure to reattach the retina and thus improve the visual acuity.

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家族性渗出性玻璃体视网膜病变患者与孔源性视网膜脱离相关的广泛视网膜下纤维化的切除。

目的：探讨家族性渗出性玻璃体视网膜病变（FEVR）伴孔源性视网膜脱离（RRD）但无牵引性视网膜脱离的广泛视网膜下纤维化（ESF）的特点和治疗方法。方法：观察RRD-FEVR患者10眼ESF，男9眼，女1眼。确定了ESF切除后的特征、手术方法和结果。通过小视网膜切除术剥离ESF，或通过bbb180°视网膜切除术或锯齿眼视网膜切除术整体切除ESF。结果：患者中位年龄为12.5岁。所有病例均有单侧黄斑脱离，4眼完全脱离，6眼超过2象限脱离。第一个病例通过小视网膜切开术进行ESF剥离，需要另外7次手术，最终视力（VA）为手部运动。随后的9例均行整体切除，以硅油填塞视网膜复位。在中位随访7年期间，硅油被移除，没有RD复发。最终VA中位数为20/66，范围为20/17至20/500。结论：发热出血热伴RRD缓慢进展的眼可见ESF。我们的结论是，整个切除ESF是一种有效和安全的手术，以重新连接视网膜，从而提高视力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Retina-The Journal of Retinal and Vitreous Diseases 医学-眼科学

CiteScore

5.70

自引率

9.10%

发文量

554

审稿时长

3-6 weeks

期刊介绍： RETINA® focuses exclusively on the growing specialty of vitreoretinal disorders. The Journal provides current information on diagnostic and therapeutic techniques. Its highly specialized and informative, peer-reviewed articles are easily applicable to clinical practice. In addition to regular reports from clinical and basic science investigators, RETINA® publishes special features including periodic review articles on pertinent topics, special articles dealing with surgical and other therapeutic techniques, and abstract cards. Issues are abundantly illustrated in vivid full color. Published 12 times per year, RETINA® is truly a “must have” publication for anyone connected to this field.