Resurgent multistate measles outbreak in Sudan amidst conflict: Urgent need for vaccination and international support.

IF 4.3 2区医学 Q1 INFECTIOUS DISEASES

International Journal of Infectious Diseases Pub Date : 2025-09-13 DOI:10.1016/j.ijid.2025.108066

Ayman Azhary, Nooh Mohamed Hajhamed, Eman Taha Osman Ali, Claude Mambo Muvunyi, Emmanuel Edwar Siddig

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引用次数: 0

Abstract

Objectives: This study assesses the epidemiological trends of a multistate measles outbreak in Sudan amidst ongoing armed conflict, highlighting the urgent need for enhanced vaccination efforts and international support.

Methods: A retrospective cross-sectional analysis was conducted using national surveillance data collected from January 2024 to June 2025. Epidemiological parameters, including case counts, fatalities, and vaccination coverage, were calculated and analyzed with R software 4.2.2 (Version 2025.05.1 + 513).

Results: A total of 3563 measles cases and 20 deaths were reported across 13 states. North Darfur recorded the highest number of cases (n = 1760), followed by Khartoum (n = 553) and River Nile (n = 380). The overall case fatality rate (CFR) decreased from 1.27% in 2024 to 0.28% in the first half of 2025. Vaccination coverage remained low in several hotspots, with notable deficits in displaced populations worsened by logistics disruptions. The resurgence emphasizes gaps in immunization coverage and underscores the impact of conflict-related healthcare infrastructure deterioration.

Conclusions: The re-emergence of measles across multiple regions during Sudan's conflict underscores an urgent need for targeted mass vaccination campaigns, strengthened disease surveillance, and international assistance. Addressing these vulnerabilities is crucial to preventing future outbreaks and safeguarding vulnerable populations, particularly children and displaced communities.

查看原文本刊更多论文

冲突中苏丹多州麻疹疫情再次爆发：迫切需要疫苗接种和国际支持。

目的：本研究评估了苏丹在持续武装冲突中多州麻疹暴发的流行病学趋势，强调了加强疫苗接种工作和国际支持的迫切需要。方法：对2024年1月至2025年6月收集的全国监测数据进行回顾性横断面分析。使用R软件4.2.2 （Version 2025.05.1+513）计算和分析流行病学参数，包括病例数、死亡人数和疫苗接种覆盖率。结果：13个州共报告了3,563例麻疹病例和20例死亡。北达尔富尔记录的病例最多（n=1,760），其次是喀土穆（n=553）和尼罗河（n=380）。总病死率（CFR）从2024年的1.27%下降到2025年上半年的0.28%。在一些热点地区，疫苗接种覆盖率仍然很低，在流离失所人口中疫苗接种明显不足，物流中断使情况进一步恶化。疫情的再次爆发凸显了免疫覆盖方面的差距，并凸显了与冲突有关的卫生保健基础设施恶化的影响。结论：在苏丹冲突期间，麻疹在多个地区重新出现，这突显出迫切需要开展有针对性的大规模疫苗接种运动、加强疾病监测和国际援助。解决这些脆弱性对于预防未来疫情爆发和保护弱势群体，特别是儿童和流离失所社区至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Infectious Diseases 医学-传染病学

CiteScore

18.90

自引率

2.40%

发文量

1020

审稿时长

30 days

期刊介绍： International Journal of Infectious Diseases (IJID) Publisher: International Society for Infectious Diseases Publication Frequency: Monthly Type: Peer-reviewed, Open Access Scope: Publishes original clinical and laboratory-based research. Reports clinical trials, reviews, and some case reports. Focuses on epidemiology, clinical diagnosis, treatment, and control of infectious diseases. Emphasizes diseases common in under-resourced countries.