{"title":"Advanced Multifunctional Bioactive Glass Nanoparticles: from Tissue Repair to Theranostics.","authors":"Yanzi Zhao, Weipeng Qiang, Bo Lei","doi":"10.1002/adhm.202502192","DOIUrl":null,"url":null,"abstract":"<p><p>In recent years, multifunctional bioactive glass nanoparticles (BGNs) have received widespread attention in biomedical applications due to their highly bioactive properties, nanoscale structure, and various functions (tissue repair, bioimaging, tumor therapy, and anti-infection). This work reviews the recent progress of multifunctional BGNs on the physicochemical structure, preparation methods, functionalizing strategies, and biomedical applications from tissue repair to theranostics. The applications of functional BGNs in tissue repair, bioimaging, drug delivery, gene delivery, anti-infection therapy, tumor intervention, and the integrated therapeutic-repair platform are carefully summarized. Through the comprehensive analysis of multifunctional BGNs in terms of structural design, functional construction, and biomedical applications, the systematic references and theoretical support for the multidimensional optimization and precise clinical translations are provided.</p>","PeriodicalId":113,"journal":{"name":"Advanced Healthcare Materials","volume":" ","pages":"e02192"},"PeriodicalIF":9.6000,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Healthcare Materials","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1002/adhm.202502192","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0
Abstract
In recent years, multifunctional bioactive glass nanoparticles (BGNs) have received widespread attention in biomedical applications due to their highly bioactive properties, nanoscale structure, and various functions (tissue repair, bioimaging, tumor therapy, and anti-infection). This work reviews the recent progress of multifunctional BGNs on the physicochemical structure, preparation methods, functionalizing strategies, and biomedical applications from tissue repair to theranostics. The applications of functional BGNs in tissue repair, bioimaging, drug delivery, gene delivery, anti-infection therapy, tumor intervention, and the integrated therapeutic-repair platform are carefully summarized. Through the comprehensive analysis of multifunctional BGNs in terms of structural design, functional construction, and biomedical applications, the systematic references and theoretical support for the multidimensional optimization and precise clinical translations are provided.
期刊介绍：
Advanced Healthcare Materials, a distinguished member of the esteemed Advanced portfolio, has been dedicated to disseminating cutting-edge research on materials, devices, and technologies for enhancing human well-being for over ten years. As a comprehensive journal, it encompasses a wide range of disciplines such as biomaterials, biointerfaces, nanomedicine and nanotechnology, tissue engineering, and regenerative medicine.
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