Evaluation of Phaseolus vulgaris lec- lpa as Alternative Protein Source on Growth Performances, Health Status, Faecal Minerals and Gut Microbiota in Weaned Piglet's Diet.

IF 1.7 3区农林科学 Q2 VETERINARY SCIENCES

Veterinary Medicine and Science Pub Date : 2025-09-01 DOI:10.1002/vms3.70597

Benedetta Canala, Sara Frazzini, Matteo Dell'Anno, Matteo Santoru, Irene Ferri, Francesca Sparvoli, Lucrezia Luciani, Bianca Castiglioni, Paola Cremonesi, Filippo Biscarini, Martina Ghidoli, Roberto Pilu, Luciana Rossi

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Abstract

Background: Genetically modified soybean is largely used in animal feed and its massive cultivation affects the environmental sustainability of livestock and the dependency for the import in the European market.

Objectives: The aim of this study was to evaluate the partial substitution of soybean meal with an innovative common bean genotype (Phaseolus vulgaris lec-lpa) with reduced content of anti-nutritional factors on zootechnical performance, gut microbiota modulation and faecal minerals in post-weaning piglets.

Methods: Fourteen piglets were divided into a control group fed with a basal diet and a treatment group fed with a commercial diet in which 7.3% of soybean meal and 0.8% of soybean oil were replaced with 10% of P. vulgaris lec- lpa for 28 days. BW, ADG, ADFI and FCR were evaluated, and diarrhoea incidence was recorded. Evaluation of pH, nitrogen content, protein digestibility and mineral content was performed on faecal samples. Microbiota was analysed by rectal swabs samples. Blood serum metabolic profile was evaluated.

Results: The treatment group showed lower BW and ADG during the trial (p < 0.05), but the health status of the animals was preserved. The treatment group released lower levels of minerals in faeces when compared with the control group after 28 days (p < 0.05) suggesting a lower dispersion of faecal minerals in the environment. Significant Beta diversity index was observed at 14 and 28 days (p < 0.05). Roseburia and Butyricicoccus increased in treatment group at day 28 (p < 0.05). These genera are associated with SCFA production, contributing to the maintenance of intestinal integrity, promoting positive bacterial populations and limiting inflammatory phenomena.

Conclusions: In conclusion, P. vulgaris lec- lpa could be a viable and sustainable alternative protein source to reduce the European protein gap, playing a potential role in microbiota modulation and faecal minerals release.

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菜豆卵磷脂作为替代蛋白质源对断奶仔猪生长性能、健康状况、粪便矿物质和肠道微生物群的影响

背景：转基因大豆主要用于动物饲料，其大规模种植影响了牲畜的环境可持续性和对欧洲市场进口的依赖。目的：本研究旨在评估一种新型普通大豆基因型（Phaseolus vulgaris lecl -lpa）部分替代豆粕对断奶后仔猪动物生产性能、肠道菌群调节和粪便矿物质含量的影响。方法：将14头仔猪分为对照组和试验组，分别饲喂基础饲粮和试验组，试验期28 d，试验组饲粮中添加10%的豆粕多糖，替代7.3%的豆粕和0.8%的豆油。测定体重、平均日增重、平均日增重和总肥力，并记录腹泻发生率。对粪便样品进行pH、氮含量、蛋白质消化率和矿物质含量的评价。用直肠拭子样本分析微生物群。测定血清代谢谱。结果：治疗组在试验期间体重和平均日增重明显降低（p < 0.05），但动物的健康状况保持不变。28天后，与对照组相比，治疗组在粪便中释放的矿物质含量较低（p < 0.05），表明粪便中矿物质在环境中的分散程度较低。第14、28 d β多样性指数显著（p < 0.05）。治疗组第28天玫瑰菌和丁酸梭菌增多（p < 0.05）。这些属与短链脂肪酸的产生有关，有助于维持肠道完整性，促进阳性细菌数量和限制炎症现象。结论：综上所述，P. vulgaris lec- lpa可能是一种可行且可持续的替代蛋白质来源，可以减少欧洲蛋白缺口，并在微生物群调节和粪便矿物质释放中发挥潜在作用。

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来源期刊

Veterinary Medicine and Science Veterinary-General Veterinary

CiteScore

3.00

自引率

0.00%

发文量

296

期刊介绍： Veterinary Medicine and Science is the peer-reviewed journal for rapid dissemination of research in all areas of veterinary medicine and science. The journal aims to serve the research community by providing a vehicle for authors wishing to publish interesting and high quality work in both fundamental and clinical veterinary medicine and science. Veterinary Medicine and Science publishes original research articles, systematic reviews, meta-analyses, and research methods papers, along with invited editorials and commentaries. Original research papers must report well-conducted research with conclusions supported by the data presented in the paper. We aim to be a truly global forum for high-quality research in veterinary medicine and science, and believe that the best research should be published and made widely accessible as quickly as possible. Veterinary Medicine and Science publishes papers submitted directly to the journal and those referred from a select group of prestigious journals published by Wiley-Blackwell. Veterinary Medicine and Science is a Wiley Open Access journal, one of a new series of peer-reviewed titles publishing quality research with speed and efficiency. For further information visit the Wiley Open Access website.