The chromosomal genome sequence of the photosymbiotic ascidian, Trididemnum clinides Kott, 1977 and its associated microbial metagenome sequences.

Q1 Medicine
Wellcome Open Research Pub Date : 2025-10-06 eCollection Date: 2025-01-01 DOI:10.12688/wellcomeopenres.24563.2
Euichi Hirose, Jose Victor Lopez, Graeme Oatley, Elizabeth Sinclair, Eerik Aunin, Noah Gettle, Camilla Santos, Michael Paulini, Haoyu Niu, Victoria McKenna, Rebecca O'Brien
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引用次数: 0

Abstract

We present a genome assembly from a specimen of Trididemnum clinides (photosymbiotic ascidian; Chordata; Ascidiacea; Aplousobranchia; Didemnidae). The T. clinides genome sequence has a total length of 906.92 megabases. Most of the assembly (97.83%) is scaffolded into 23 chromosomal pseudomolecules. The mitochondrial genome has also been assembled and is 14.98 kilobases in length. The host ascidian has multiple symbionts, including Prochloron, a cyanobacterial genus that can also synthesise bioactive natural products of interest for potential therapeutic development. Biosynthesis of active compounds sometimes involves microbial associates.

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光共生海鞘(Trididemnum clinides Kott, 1977)染色体基因组序列及其相关微生物元基因组序列。
我们提出了一个来自trididemum clinides(光共生海鞘;脊索目;海鞘科;Aplousobranchia;双海胆科)标本的基因组组装。T. clinides基因组序列总长度为906.92兆碱基。大部分(97.83%)组装成23个染色体假分子。线粒体基因组也已组装完成,全长14.98千碱基。宿主海鞘有多种共生体,包括Prochloron,这是一种细菌属,也可以合成具有生物活性的天然产物,用于潜在的治疗开发。活性化合物的生物合成有时涉及微生物。
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来源期刊
Wellcome Open Research
Wellcome Open Research Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)
CiteScore
5.50
自引率
0.00%
发文量
426
审稿时长
1 weeks
期刊介绍: Wellcome Open Research publishes scholarly articles reporting any basic scientific, translational and clinical research that has been funded (or co-funded) by Wellcome. Each publication must have at least one author who has been, or still is, a recipient of a Wellcome grant. Articles must be original (not duplications). All research, including clinical trials, systematic reviews, software tools, method articles, and many others, is welcome and will be published irrespective of the perceived level of interest or novelty; confirmatory and negative results, as well as null studies are all suitable. See the full list of article types here. All articles are published using a fully transparent, author-driven model: the authors are solely responsible for the content of their article. Invited peer review takes place openly after publication, and the authors play a crucial role in ensuring that the article is peer-reviewed by independent experts in a timely manner. Articles that pass peer review will be indexed in PubMed and elsewhere. Wellcome Open Research is an Open Research platform: all articles are published open access; the publishing and peer-review processes are fully transparent; and authors are asked to include detailed descriptions of methods and to provide full and easy access to source data underlying the results to improve reproducibility.
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