Content Validity of the Hemophilia Device Handling and Preference Assessment Questionnaire - A Cognitive Debrief Study in Patients with Hemophilia and Their Caregivers.
Niklas Kahr Rasmussen, Sanket Shah, Jui-Hua Tsai, Kelly P McCarrier, Emily A Hildebrand, Maya Gonczi, Gitte Ter-Borch, Birgitte Berg, Jesper Skov Neergaard
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引用次数: 0
Abstract
Introduction: As new treatment options using different modes of administration become available for patients with hemophilia, it is important to assess how patients and caregivers perceive the use of different injection systems.
Aim: This study aimed to evaluate patient comprehension, relevance, and comprehensiveness of the Hemophilia Device Handling and Preference Assessment (HDHPA) instrument among the hemophilia population. Specifically, cognitive interviews were to be conducted to establish evidence of the content validity for the instrument's use in a handling and preference study.
Methods: This cross-sectional interview study included participants randomly selected from a pen-injector handling and preference study in the USA who had self-administered a ten-item HDHPA questionnaire. Subsequently, semi-structured cognitive interviews were conducted examining HDHPA instrument instructions, items, and response options.
Results: The study sample consisted of 20 participants (50% adult patients, 25% adolescents, and 25% caregivers; 75% male). Most participants (89-100%) demonstrated comprehension of the instructions given. Nearly all participants (94-100%) demonstrated clear comprehension of the ten HDHPA items. All 20 participants stated that the questionnaire was relevant and comprehensive in assessing the pen-injector and comparing it to their current device.
Conclusion: The results of this study showed that the HDHPA items are comprehensible, relevant, and comprehensive, thereby confirming the content validity of this instrument.
期刊介绍:
Patient Preference and Adherence is an international, peer reviewed, open access journal that focuses on the growing importance of patient preference and adherence throughout the therapeutic continuum. The journal is characterized by the rapid reporting of reviews, original research, modeling and clinical studies across all therapeutic areas. Patient satisfaction, acceptability, quality of life, compliance, persistence and their role in developing new therapeutic modalities and compounds to optimize clinical outcomes for existing disease states are major areas of interest for the journal.
As of 1st April 2019, Patient Preference and Adherence will no longer consider meta-analyses for publication.