{"title":"Ovarian hyperstimulation revealing a functional gonadotroph adenoma: a case report.","authors":"Amel Rahal, Toufik Bennafaa, Hanane Kherrab, Nassima Djennane, Malha Azzouz","doi":"10.11604/pamj.2025.51.57.47982","DOIUrl":null,"url":null,"abstract":"<p><p>We report the case of a functional gonadotropic adenoma (FGA) in a 32-year-old woman, initially revealed by ovarian hyperstimulation. Hormonal investigations strongly suggested an FGA; pelvic ultrasound revealed macrofollicular ovarian enlargement. Despite a clear clinical picture, diagnosis was delayed until the appearance of cranial tumor syndrome with ophthalmological impairment and pituitary dysfunction. The ophthalmological emergency necessitated urgent surgery, allowing both decompression of the optic pathways and a reduction in hyperestrogenism. Despite their rarity, it is essential to recognize FGA to avoid potentially fatal complications.</p>","PeriodicalId":48190,"journal":{"name":"Pan African Medical Journal","volume":"51 ","pages":"57"},"PeriodicalIF":1.0000,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12433010/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pan African Medical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.11604/pamj.2025.51.57.47982","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
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Abstract
We report the case of a functional gonadotropic adenoma (FGA) in a 32-year-old woman, initially revealed by ovarian hyperstimulation. Hormonal investigations strongly suggested an FGA; pelvic ultrasound revealed macrofollicular ovarian enlargement. Despite a clear clinical picture, diagnosis was delayed until the appearance of cranial tumor syndrome with ophthalmological impairment and pituitary dysfunction. The ophthalmological emergency necessitated urgent surgery, allowing both decompression of the optic pathways and a reduction in hyperestrogenism. Despite their rarity, it is essential to recognize FGA to avoid potentially fatal complications.
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