Influence of Baoyuan decoction and Taohong Siwu decoction combined with Western medicine on serum lipid levels in elderly patients with coronary heart disease.

Abstract

Background: To explore how Baoyuan and Taohong Siwu decoctions combined with Western medicine affect triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) in elderly patients with coronary heart disease.

Methods: Ninety elderly patients with coronary heart disease who were hospitalized from January 2021 to December 2022 were selected and divided into two groups based on different treatment methods, with 45 patients in each group. The control group was treated with Western medicine alone, while the research group was treated with the combination of Baoyuan and Taohong Siwu decoctions based on the control group. The improvement of traditional Chinese medicine symptom scores, various blood lipid levels, and serum indicators of cardiac function were compared between two groups before treatment, 1 month, 2 months, and 3 months of treatment.

Results: Before treatment, the two groups had identical Traditional Chinese Medicine symptom scores, various blood lipid levels, and various serum indicators of cardiac function (P> 0.05). After treating 1 month, 2 months, and 3 months, the chest pain, tightness, fatigue, and sweating scores in the research group were lower (P< 0.05). The TG, TC, LDL-C, and HDL-C levels in the research group were lower (P< 0.05). The levels of plasma N-terminal brain natriuretic peptide (NT-proBNP) and monocyte chemoattractant protein-1 (MCP-1) in the research group were lower (P <0.05).

Conclusions: Combining Baoyuan and Taohong Siwu decoctions and Western medicine treatment can help improve the symptoms and signs of coronary heart disease in the elderly. It can reduce the levels of various indicators such as LDL-C, TG, TC, and HDL-C in the body and promote the improvement of cardiac function.