Thyroid Cancer Detection Using Py-SpinalNet: A Pyramid and SpinalNet Approach.

IF 1.9 4区 医学 Q3 ONCOLOGY
Cancer Investigation Pub Date : 2025-08-01 Epub Date: 2025-09-15 DOI:10.1080/07357907.2025.2543853
Murugadoss R, Augustus Devarajan A, Vetriselvi T, Rajanarayanan S
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引用次数: 0

Abstract

Currently, thyroid cancer and thyroid nodules disorders are increasing globally. The diagnosis of these conditions relies on the development of medical technology. Current methods often suffer from the overfitting issue due to a small dataset and a lack of generalizability to diverse clinical settings. Some of the traditional methods encounter challenges with false positive and false negative rates, which affects the performance of the model. To overcome these challenges, a novel module called Pyramid-SpinalNet (Py-SpinalNet) has been developed for thyroid cancer classification. From the given database, the image is pre-processed through the Wiener filter. After this, 3D-UNet is employed for nodule segmentation. In addition, key features are derived through the process of feature extraction. Eventually, the Py-SpinalNet is used for the classification of thyroid cancer. The Py-SpinalNet is developed by merging PyramidNet and SpinalNet. Here, Accuracy, True Positive Rate (TPR), and True Negative Rate (TNR) are the metrics employed for Py-SpinalNet acquired 91.9, 90.9 and 92.8%. The Py-SpinalNet model can accurately detect thyroid cancer at the early stage, thereby minimizing both false-positive and false-negative rates. Thus, it offers a more efficient and reliable classification of thyroid cancer.

使用Py-SpinalNet检测甲状腺癌:金字塔和SpinalNet方法。
目前,甲状腺癌和甲状腺结节疾病在全球范围内呈上升趋势。这些疾病的诊断依赖于医学技术的发展。由于数据集小,缺乏对不同临床环境的通用性,目前的方法经常遭受过拟合问题。一些传统的方法遇到了假阳性和假阴性率的挑战,影响了模型的性能。为了克服这些挑战,开发了一种名为Pyramid-SpinalNet (Py-SpinalNet)的新型模块,用于甲状腺癌分类。从给定的数据库中,通过维纳滤波对图像进行预处理。之后,采用3D-UNet进行结节分割。此外,通过特征提取过程导出关键特征。最终,Py-SpinalNet被用于甲状腺癌的分类。Py-SpinalNet是由PyramidNet和SpinalNet合并而成的。在这里,准确率、真阳性率(TPR)和真阴性率(TNR)是Py-SpinalNet采用的指标,分别获得了91.9、90.9和92.8%。Py-SpinalNet模型可以在早期准确发现甲状腺癌,从而最大限度地减少假阳性和假阴性率。因此,它提供了一个更有效和可靠的甲状腺癌分类。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Cancer Investigation
Cancer Investigation 医学-肿瘤学
CiteScore
3.80
自引率
4.20%
发文量
71
审稿时长
8.5 months
期刊介绍: Cancer Investigation is one of the most highly regarded and recognized journals in the field of basic and clinical oncology. It is designed to give physicians a comprehensive resource on the current state of progress in the cancer field as well as a broad background of reliable information necessary for effective decision making. In addition to presenting original papers of fundamental significance, it also publishes reviews, essays, specialized presentations of controversies, considerations of new technologies and their applications to specific laboratory problems, discussions of public issues, miniseries on major topics, new and experimental drugs and therapies, and an innovative letters to the editor section. One of the unique features of the journal is its departmentalized editorial sections reporting on more than 30 subject categories covering the broad spectrum of specialized areas that together comprise the field of oncology. Edited by leading physicians and research scientists, these sections make Cancer Investigation the prime resource for clinicians seeking to make sense of the sometimes-overwhelming amount of information available throughout the field. In addition to its peer-reviewed clinical research, the journal also features translational studies that bridge the gap between the laboratory and the clinic.
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