Murugadoss R, Augustus Devarajan A, Vetriselvi T, Rajanarayanan S
{"title":"Thyroid Cancer Detection Using Py-SpinalNet: A Pyramid and SpinalNet Approach.","authors":"Murugadoss R, Augustus Devarajan A, Vetriselvi T, Rajanarayanan S","doi":"10.1080/07357907.2025.2543853","DOIUrl":null,"url":null,"abstract":"<p><p>Currently, thyroid cancer and thyroid nodules disorders are increasing globally. The diagnosis of these conditions relies on the development of medical technology. Current methods often suffer from the overfitting issue due to a small dataset and a lack of generalizability to diverse clinical settings. Some of the traditional methods encounter challenges with false positive and false negative rates, which affects the performance of the model. To overcome these challenges, a novel module called Pyramid-SpinalNet (Py-SpinalNet) has been developed for thyroid cancer classification. From the given database, the image is pre-processed through the Wiener filter. After this, 3D-UNet is employed for nodule segmentation. In addition, key features are derived through the process of feature extraction. Eventually, the Py-SpinalNet is used for the classification of thyroid cancer. The Py-SpinalNet is developed by merging PyramidNet and SpinalNet. Here, Accuracy, True Positive Rate (TPR), and True Negative Rate (TNR) are the metrics employed for Py-SpinalNet acquired 91.9, 90.9 and 92.8%. The Py-SpinalNet model can accurately detect thyroid cancer at the early stage, thereby minimizing both false-positive and false-negative rates. Thus, it offers a more efficient and reliable classification of thyroid cancer.</p>","PeriodicalId":9463,"journal":{"name":"Cancer Investigation","volume":" ","pages":"569-593"},"PeriodicalIF":1.9000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cancer Investigation","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/07357907.2025.2543853","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/9/15 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Currently, thyroid cancer and thyroid nodules disorders are increasing globally. The diagnosis of these conditions relies on the development of medical technology. Current methods often suffer from the overfitting issue due to a small dataset and a lack of generalizability to diverse clinical settings. Some of the traditional methods encounter challenges with false positive and false negative rates, which affects the performance of the model. To overcome these challenges, a novel module called Pyramid-SpinalNet (Py-SpinalNet) has been developed for thyroid cancer classification. From the given database, the image is pre-processed through the Wiener filter. After this, 3D-UNet is employed for nodule segmentation. In addition, key features are derived through the process of feature extraction. Eventually, the Py-SpinalNet is used for the classification of thyroid cancer. The Py-SpinalNet is developed by merging PyramidNet and SpinalNet. Here, Accuracy, True Positive Rate (TPR), and True Negative Rate (TNR) are the metrics employed for Py-SpinalNet acquired 91.9, 90.9 and 92.8%. The Py-SpinalNet model can accurately detect thyroid cancer at the early stage, thereby minimizing both false-positive and false-negative rates. Thus, it offers a more efficient and reliable classification of thyroid cancer.
期刊介绍:
Cancer Investigation is one of the most highly regarded and recognized journals in the field of basic and clinical oncology. It is designed to give physicians a comprehensive resource on the current state of progress in the cancer field as well as a broad background of reliable information necessary for effective decision making. In addition to presenting original papers of fundamental significance, it also publishes reviews, essays, specialized presentations of controversies, considerations of new technologies and their applications to specific laboratory problems, discussions of public issues, miniseries on major topics, new and experimental drugs and therapies, and an innovative letters to the editor section. One of the unique features of the journal is its departmentalized editorial sections reporting on more than 30 subject categories covering the broad spectrum of specialized areas that together comprise the field of oncology. Edited by leading physicians and research scientists, these sections make Cancer Investigation the prime resource for clinicians seeking to make sense of the sometimes-overwhelming amount of information available throughout the field. In addition to its peer-reviewed clinical research, the journal also features translational studies that bridge the gap between the laboratory and the clinic.