Do monocortical distal locking screws impair mechanical properties in opening wedge high tibial osteotomy with bone graft?-a sawbone biomechanical study.
Pei Yi Loh, Xuanrong Michael Shen, Siaw Meng Chou, You Xiang Chang, Vikaesh Moorthy, Hamid Rahmatullah Bin Abd Razak
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引用次数: 0
Abstract
Medial opening wedge high tibial osteotomy (MOWHTO) has gained popularity for treating patients with medial knee osteoarthritis. Bicortical screw fixation is conventionally preferred, but its mechanical advantage over monocortical fixation remains elusive clinically, and may have additional symptomatic hardware risks. Our study aimed to quantify mechanical differences between monocortical and bicortical distal screws construct in MOWHTO. Twenty artificial composite tibiae were used, with 10 specimens per arm. The first arm underwent MOWHTO with bicortical screw fixation throughout; the second arm incorporated two monocortical distal locking screws. Mechanical properties of specimens were evaluated with static compressive load-bearing till failure and cyclic fatigue strength testing. For quasi-static compression testing, monocortical specimens had a median ultimate load of 2.60 [interquartile range (IQR)=0.12] kN [mean ± standard deviation (SD) =2.59±0.15 kN], comparable to the bicortical group [median (IQR) =2.64 (0.46) kN, mean ± SD =2.56±0.33 kN]. Cyclic fatigue strength testing also demonstrated comparable maximal loads tolerated by both monocortical [median (IQR) =1.28 (0.08) kN, mean ± SD =1.33±0.12 kN] and bicortical [median (IQR) =1.28 (0.00) kN, mean ± SD =1.28±0.06 kN] specimens, as well as median number of cycles attained before failure. Mann-Whitney-U tests showed no statistically significant difference for all measured outcomes between monocortical and bicortical groups (P>0.05). Our study found monocortical fixation of the two distal-most screws in MOWHTO mechanically non-inferior to bicortical fixation. This supports monocortical fixation as an alternative technique for distal screw placement in MOWHTO.
期刊介绍:
The Annals of Translational Medicine (Ann Transl Med; ATM; Print ISSN 2305-5839; Online ISSN 2305-5847) is an international, peer-reviewed Open Access journal featuring original and observational investigations in the broad fields of laboratory, clinical, and public health research, aiming to provide practical up-to-date information in significant research from all subspecialties of medicine and to broaden the readers’ vision and horizon from bench to bed and bed to bench. It is published quarterly (April 2013- Dec. 2013), monthly (Jan. 2014 - Feb. 2015), biweekly (March 2015-) and openly distributed worldwide. Annals of Translational Medicine is indexed in PubMed in Sept 2014 and in SCIE in 2018. Specific areas of interest include, but not limited to, multimodality therapy, epidemiology, biomarkers, imaging, biology, pathology, and technical advances related to medicine. Submissions describing preclinical research with potential for application to human disease, and studies describing research obtained from preliminary human experimentation with potential to further the understanding of biological mechanism underlying disease are encouraged. Also warmly welcome are studies describing public health research pertinent to clinic, disease diagnosis and prevention, or healthcare policy. With a focus on interdisciplinary academic cooperation, ATM aims to expedite the translation of scientific discovery into new or improved standards of management and health outcomes practice.