Incidence and risk factor evaluation for postoperative nausea and vomiting in cesarean section under general anesthesia compared to the gynecologic surgery: A retrospective study

IF 1.5 4区医学 Q3 OBSTETRICS & GYNECOLOGY

Journal of Obstetrics and Gynaecology Research Pub Date : 2025-09-15 DOI:10.1111/jog.70074

Su Yeon Kim, Seukyoung Hong, Jung-Won Hwang, Sang-Hwan Do, Hyo-Seok Na

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Abstract

Aim

This retrospective study sought to investigate the incidence of postoperative nausea and vomiting (PONV) and its associated risk factors in patients undergoing cesarean section under general anesthesia.

Methods

Patients who underwent cesarean section under general anesthesia or who underwent open gynecologic surgery were assigned to the OB group (n = 291) or the GY group (n = 225), respectively. The primary outcome was the incidence of PONV. Multivariable logistic regression analysis was performed to identify independent risk factors for PONV in the OB group. Propensity score matching was additionally conducted to facilitate a comparison of PONV incidence between the OB and GY groups (n = 66 in each group).

Results

In the OB group, 21 patients (7.2%) experienced PONV, which was significantly lower than the 68 patients (30.2%) in the GY group (p < 0.001). This difference remained statistically significant after propensity score matching (15.2% in the OB group vs. 31.8% in the GY group; p = 0.019). In multivariable logistic regression analysis of the OB group, abdominal surgical history (p = 0.032), longer surgical duration (p = 0.017), lower fluid intake (p = 0.011), and higher estimated blood loss (p = 0.009) were associated with PONV.

Conclusions

PONV may occur less frequently in patients undergoing cesarean section under general anesthesia than in those undergoing gynecologic surgery. In obstetric patients, substantial intraoperative blood loss with inadequate fluid replacement, prolonged surgical duration, and a history of abdominal surgery may represent additional risk factor for PONV.

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全麻剖宫产术与妇科手术术后恶心呕吐发生率及危险因素评价：一项回顾性研究

目的探讨全麻剖宫产术患者术后恶心呕吐（PONV）的发生率及其相关危险因素。方法将全麻剖宫产术患者和妇科开腹手术患者分别分为OB组（291例）和GY组（225例）。主要终点是PONV的发生率。采用多变量logistic回归分析确定OB组PONV的独立危险因素。另外进行倾向评分匹配，以便比较OB组和GY组之间PONV发生率（每组n = 66）。结果OB组PONV发生率为21例（7.2%），显著低于GY组68例（30.2%）（p < 0.001）。倾向评分匹配后，这一差异仍具有统计学意义（OB组15.2% vs GY组31.8%,p = 0.019）。在OB组的多变量logistic回归分析中，腹部手术史（p = 0.032）、较长的手术时间（p = 0.017）、较低的液体摄入量（p = 0.011）和较高的估计失血量（p = 0.009）与PONV相关。结论全麻剖宫产术患者PONV发生率低于妇科手术患者。在产科患者中，术中大量失血，补液不足，手术时间延长，腹部手术史可能是PONV的额外危险因素。

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来源期刊

Journal of Obstetrics and Gynaecology Research 医学-妇产科学

CiteScore

3.10

自引率

0.00%

发文量

376

审稿时长

3-6 weeks

期刊介绍： The Journal of Obstetrics and Gynaecology Research is the official Journal of the Asia and Oceania Federation of Obstetrics and Gynecology and of the Japan Society of Obstetrics and Gynecology, and aims to provide a medium for the publication of articles in the fields of obstetrics and gynecology. The Journal publishes original research articles, case reports, review articles and letters to the editor. The Journal will give publication priority to original research articles over case reports. Accepted papers become the exclusive licence of the Journal. Manuscripts are peer reviewed by at least two referees and/or Associate Editors expert in the field of the submitted paper.