Zhaoyi Wang, Meijun Chen, Assoc. Prof. Jiaxuan Shen
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引用次数: 0
Abstract
Pyridine cores are important heterocycles that exist in natural products, pharmaceuticals, and chiral ligands. Recently, radical-based 4-cyanopyridine has an effective approach for the synthesis of complex pyridines. In this review, we provide an overview of the recent development of multicomponent reactions using 4-cyanopyridine as pyridylation reagent for rapidly constructing complex molecules, including pyridine core. We systematically classified the recent literatures in the field based on bonding type, including C─C or C-heteroatom. This review aims to highlight the results of 4-cyanopyridine as a powerful pyridylation reagent for multicomponent reactions.
期刊介绍：
Organic chemistry is the fundamental science that stands at the heart of chemistry, biology, and materials science. Research in these areas is vigorous and truly international, with three major regions making almost equal contributions: America, Europe and Asia. Asia now has its own top international organic chemistry journal—the Asian Journal of Organic Chemistry (AsianJOC)
The AsianJOC is designed to be a top-ranked international research journal and publishes primary research as well as critical secondary information from authors across the world. The journal covers organic chemistry in its entirety. Authors and readers come from academia, the chemical industry, and government laboratories.
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