Effects of timing and duration of stepwise vitamin–mineral premix withdrawal on welfare indicators and trace mineral excretion in broilers

IF 1.9 3区农林科学 Q2 AGRICULTURE, DAIRY & ANIMAL SCIENCE

Livestock Science Pub Date : 2025-09-08 DOI:10.1016/j.livsci.2025.105821

S. Siahpour , M.A.Karimi Torshizi , O. Jangjou , H. Saleh

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引用次数: 0

Abstract

Trace mineral supplementation via vitamin–mineral premixes (VMP) is essential for broiler health and productivity but may contribute to environmental pollution through excessive mineral excretion. This study investigated the effects of time-based VMP withdrawal at different production stages on growth performance, bone mineralization, immune function, antioxidant capacity, welfare indicators, and zinc and copper excretion in broilers. A total of 500 one-day-old male Ross 308 chicks were allocated to five dietary treatments (five replicates per treatment; 20 birds/replicate) in a completely randomized design over 42days. Treatments consisted of a control group (VMP fed for 42 days) and four time-dependent withdrawal groups, where VMP was removed for the final 7, 14, 21, and 28 days of the trial. Growth performance, tibia characteristics, leg condition, serum immunoglobulins (IgM, IgG, IgA), cytokines (IL-10, IL-6, IL-1β), antioxidant enzymes (CAT, SOD, GPx), total antioxidant capacity, malondialdehyde (MDA), and fecal mineral excretion were measured. Data were analyzed using a general linear model with Tukey’s test (P < 0.05) Results showed that earlier VMP withdrawal impaired growth, bone integrity, immunity, and antioxidant status while increasing feed conversion ratio, pro-inflammatory cytokines, MDA levels, and gait abnormalities. However, zinc and copper excretion decreased progressively as withdrawal occurred earlier. These findings suggest that strategically timed VMP withdrawal during the final production phase may reduce environmental impact without compromising broiler health, offering a practical and sustainable mineral management strategy.

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逐步停用维生素矿物质预混料的时间和持续时间对肉鸡福利指标和微量矿物质排泄的影响

通过维生素矿物质预混料（VMP）补充微量矿物质对肉鸡的健康和生产至关重要，但过量的矿物质排泄可能导致环境污染。本试验旨在研究不同生产阶段VMP停饲对肉仔鸡生长性能、骨矿化、免疫功能、抗氧化能力、福利指标及锌铜排泄的影响。试验采用完全随机设计，将500只1日龄雄性罗斯308雏鸡分为5个饲粮处理（每个处理5个重复，每个重复20只鸡），试验期42d。治疗包括一个对照组（VMP喂养42天）和四个时间依赖性戒断组，其中VMP在试验的最后7,14,21和28天被移除。测定生长性能、胫骨特征、腿部状况、血清免疫球蛋白（IgM、IgG、IgA）、细胞因子（IL-10、IL-6、IL-1β）、抗氧化酶（CAT、SOD、GPx）、总抗氧化能力、丙二醛（MDA）和粪便矿物质排泄量。数据采用Tukey检验的一般线性模型进行分析（P < 0.05）。结果显示，早期停用VMP会损害生长、骨完整性、免疫力和抗氧化能力，同时增加饲料转化率、促炎细胞因子、MDA水平和步态异常。然而，随着停药时间的提前，锌和铜的排泄量逐渐减少。这些发现表明，在最终生产阶段有策略地定时退出VMP可能会减少对环境的影响，而不会损害肉鸡的健康，提供了一种实用和可持续的矿物管理策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Livestock Science 农林科学-奶制品与动物科学

CiteScore

4.30

自引率

5.60%

发文量

237

审稿时长

3 months

期刊介绍： Livestock Science promotes the sound development of the livestock sector by publishing original, peer-reviewed research and review articles covering all aspects of this broad field. The journal welcomes submissions on the avant-garde areas of animal genetics, breeding, growth, reproduction, nutrition, physiology, and behaviour in addition to genetic resources, welfare, ethics, health, management and production systems. The high-quality content of this journal reflects the truly international nature of this broad area of research.