Direct Vocal Fold Testosterone Injection for Treatment of Sulcus Vocalis: A Case Report.

IF 2 3区医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL

Laryngoscope Pub Date : 2025-09-13 DOI:10.1002/lary.70129

Rohith S Voora, Michelle K Tenggara, Benjamin Schiedermayer, Andrew M Vahabzadeh-Hagh

引用次数: 0

Abstract

This case report describes the use of targeted vocal fold testosterone injection as a novel, minimally invasive treatment for sulcus vocalis in a 28-year-old cisgender male with long-standing voice difficulties unresponsive to conventional therapies. He underwent two intramuscular testosterone injections into the thyroarytenoid muscle. Post-treatment, he demonstrated significant vocal improvements, including enhanced glottal competence, increased phonation time, and improved patient-reported outcomes, suggesting that androgen receptor stimulation may promote vocal fold remodeling as a potential alternative to surgical intervention.

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直接声带注射睾酮治疗声带沟1例。

本病例报告描述了靶向声带睾酮注射作为一种新颖的微创治疗方法，用于治疗一名28岁的顺性男性，该男性长期存在声音困难，对常规治疗无反应。他接受了两次肌内睾酮注射到甲状腺样肌。治疗后，他表现出明显的声音改善，包括声门能力增强，发声时间增加，患者报告的结果改善，这表明雄激素受体刺激可能促进声带重塑，作为手术干预的潜在替代方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Laryngoscope 医学-耳鼻喉科学

CiteScore

6.50

自引率

7.70%

发文量

500

审稿时长

2-4 weeks

期刊介绍： The Laryngoscope has been the leading source of information on advances in the diagnosis and treatment of head and neck disorders since 1890. The Laryngoscope is the first choice among otolaryngologists for publication of their important findings and techniques. Each monthly issue of The Laryngoscope features peer-reviewed medical, clinical, and research contributions in general otolaryngology, allergy/rhinology, otology/neurotology, laryngology/bronchoesophagology, head and neck surgery, sleep medicine, pediatric otolaryngology, facial plastics and reconstructive surgery, oncology, and communicative disorders. Contributions include papers and posters presented at the Annual and Section Meetings of the Triological Society, as well as independent papers, "How I Do It", "Triological Best Practice" articles, and contemporary reviews. Theses authored by the Triological Society’s new Fellows as well as papers presented at meetings of the American Laryngological Association are published in The Laryngoscope. • Broncho-esophagology • Communicative disorders • Head and neck surgery • Plastic and reconstructive facial surgery • Oncology • Speech and hearing defects