A Comparison of Intravenous and Oral Transmucosal Administration of Pentobarbital Sodium for Humane Euthanasia in White Leghorn Chickens (Gallus gallus domesticus).
Aiden Masri, Thomas N Tully, Katie Como, Montana Oubre, Mark A Mitchell
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引用次数: 0
Abstract
Euthanasia is a common veterinary medical procedure performed on terminally ill backyard chickens (Gallus gallus domesticus). To reduce stress for these animals, it is important to develop a euthanasia protocol that provides a rapid and humane death. For this prospective research investigation, we evaluated 2 different methods of euthanasia in chickens. Twenty-two adult female leghorn chickens were administered an intravenous (IV, n = 11) or oral transmucosal (OTM, n = 11) 602 mg/kg dose of pentobarbital sodium solution for humane euthanasia. Loss of consciousness (LOC) occurred in 95.4% (21/22) of the birds within 5 minutes. Both apnea and asystole were achieved in 100% (11/11) of the birds in the IV group and 54.5% (6/11) of the birds in the OTM group after 5 minutes; 45.5% (5/11) of the chickens in the OTM group had to be rescued. Birds administered the euthanasia solution IV were found to have faster times to LOC (Mann-Whitney U [MW]=110.5, P < 0.001), asystole (MW: 121, P < 0.001), and apnea (MW: 121, P < 0.001) compared with the OTM chickens. Overall, the OTM route for administering pentobarbital sodium in chickens resulted in a reliable LOC in all but 1 bird; however, it did not result in apnea and asystole for all birds within 5 minutes. Based on the results of this study, the OTM administration of pentobarbital sodium is not a reliable method to euthanize chickens.
安乐死是一种常见的兽医程序,对身患绝症的后院鸡(Gallus Gallus domesticus)进行安乐死。为了减轻这些动物的压力,重要的是制定一项安乐死协议,提供快速和人道的死亡。在这项前瞻性研究中,我们评估了两种不同的鸡安乐死方法。采用602 mg/kg剂量戊巴比妥钠溶液经静脉注射(IV, n = 11)或经黏膜口服(OTM, n = 11)对22只成年雌来角鸡进行人道安乐死。95.4%(21/22)的鸟类在5分钟内发生意识丧失。IV组和OTM组在5分钟后分别有100%(11/11)和54.5%(6/11)的鸟类实现呼吸暂停和无搏停止;OTM组有45.5%(5/11)的鸡需要抢救。注射安乐死液IV的鸡出现LOC (Mann-Whitney U [MW]=110.5, P < 0.001)、心脏骤停(MW: 121, P < 0.001)和呼吸暂停(MW: 121, P < 0.001)的时间比注射安乐死液IV的鸡更快。总的来说,给鸡施用戊巴比妥钠的OTM途径在除1只鸡外的所有鸡中产生可靠的LOC;然而,并不是所有的鸟类都在5分钟内出现呼吸暂停和心脏骤停。基于本研究的结果,戊巴比妥钠不是一种可靠的安乐死鸡的方法。
期刊介绍:
The Journal of Avian Medicine and Surgery is an international journal of the medicine and surgery of both captive and wild birds. Published materials include scientific articles, case reports, editorials, abstracts, new research, and book reviews.