TiTaMo medium entropy alloys with synergistic biomechanical properties for long term implantation

IF 3.5 2区医学 Q2 ENGINEERING, BIOMEDICAL

Journal of the Mechanical Behavior of Biomedical Materials Pub Date : 2025-09-06 DOI:10.1016/j.jmbbm.2025.107189

Jing Li , Xi Rao , Guannan Li , Peitao Guo , Tingting Liu , Yuan Yuan , Liqun Xu , Xianquan Jiang , Shengfeng Guo

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引用次数: 0

Abstract

Ti-based multi-principal element alloys exhibit excellent comprehensive properties and hold great promise as biomaterials for hard tissue implants. In the present study, a novel equiatomic TiTaMo medium entropy alloy (MEA) was designed and fabricated via vacuum arc melting followed by rapid solidification (cooling rate ∼10³ K/s) to address the limitations of conventional Ti-based alloys. The microstructures, mechanical properties, wear behavior and corrosion resistance in Hank's solution were thoroughly investigated. The as-cast TiTaMo MEA, characterized by a body-centered cubic structure with a lattice parameter of 3.229 Å, demonstrated a yield strength of 1230.79 MPa, an elastic modulus suitable for bone compatibility, and a plastic deformation strain exceeding 30 % under compression. Additionally, it exhibited a Vickers microhardness of approximately 471 HV. Although the overall wear resistance of the TiTaMo MEA was slightly inferior to that of Ti6Al4V, its coefficient of friction was notably lower and more stable level (μ ≈ 0.11) during the initial 200 s of testing. Moreover, in comparison with biomedical-grade pure Ti and Ti6Al4V alloy, the TiTaMo MEA displayed superior corrosion resistance with a stable passivation plateau extending beyond 4.5 V_SCE and no detectable pitting corrosion. These preliminary findings indicate that the TiTaMo MEA has significant potential as a candidate for next-generation orthopedic and dental implants.

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长期植入具有协同生物力学性能的钛钼中熵合金

钛基多主元素合金具有优良的综合性能，作为生物硬组织植入材料具有广阔的应用前景。在本研究中，通过真空电弧熔炼和快速凝固（冷却速度~ 103 K/s），设计并制备了一种新型等原子tiamo介质熵合金（MEA），以解决传统ti基合金的局限性。研究了合金在Hank’s溶液中的组织、力学性能、磨损性能和耐蚀性。铸态tiamo MEA具有体心立方结构，晶格参数为3.229 Å，屈服强度为1230.79 MPa，弹性模量适合骨相容性，压缩塑性变形应变超过30%。此外，它的维氏显微硬度约为471 HV。虽然tiamo MEA的整体耐磨性略低于Ti6Al4V，但在试验开始的200 s内，其摩擦系数明显更低且更稳定（μ≈0.11）。此外，与生物医药级纯Ti和Ti6Al4V合金相比，TiTaMo MEA具有更强的耐蚀性，钝化平台稳定延伸至4.5 VSCE以上，没有可检测到的点蚀。这些初步研究结果表明，TiTaMo MEA作为下一代骨科和牙科种植体的候选材料具有巨大的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of the Mechanical Behavior of Biomedical Materials 工程技术-材料科学：生物材料

CiteScore

7.20

自引率

7.70%

发文量

505

审稿时长

46 days

期刊介绍： The Journal of the Mechanical Behavior of Biomedical Materials is concerned with the mechanical deformation, damage and failure under applied forces, of biological material (at the tissue, cellular and molecular levels) and of biomaterials, i.e. those materials which are designed to mimic or replace biological materials. The primary focus of the journal is the synthesis of materials science, biology, and medical and dental science. Reports of fundamental scientific investigations are welcome, as are articles concerned with the practical application of materials in medical devices. Both experimental and theoretical work is of interest; theoretical papers will normally include comparison of predictions with experimental data, though we recognize that this may not always be appropriate. The journal also publishes technical notes concerned with emerging experimental or theoretical techniques, letters to the editor and, by invitation, review articles and papers describing existing techniques for the benefit of an interdisciplinary readership.