Follicular carcinoma of the thyroid with a single metastatic lesion in the skull: A case report

Q4 Medicine

Radiology Case Reports Pub Date : 2025-09-12 DOI:10.1016/j.radcr.2025.08.037

Amir Hassan Matini MD , Sam Mirfendereski MD , Akram Tajoddini MD

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Abstract

Follicular thyroid carcinoma (FTC) represents a significant subset of thyroid malignancies following papillary thyroid cancer (PTC), constituting approximately 10% of all thyroid cancers. Surgical excision of metastatic lesions remains the cornerstone of treatment due to its potential for cure, symptom relief, and favorable response to radioactive iodine therapy. We present an exceedingly rare case involving a 79-year-old woman with a history of thyroidectomy 18 years prior, who presented to our hospital, Kashan Shahid Beheshti Hospital, with metastatic follicular thyroid carcinoma to the skull. FTC is characterized by early hematogenous spread, with the bone representing a typical site of metastasis. In patients diagnosed with FTC, large tumor size and presence of bone metastases are indicative of poor prognostic factors. However, the presence of a solitary bone metastasis should not preclude aggressive therapeutic interventions. Appropriate management strategies can lead to improved outcomes and enhanced quality of life for affected individuals.

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甲状腺滤泡癌伴颅骨单一转移病灶1例报告

滤泡性甲状腺癌（FTC）是继乳头状甲状腺癌（PTC）之后的一个重要的甲状腺恶性肿瘤子集，约占所有甲状腺癌的10%。手术切除转移性病灶仍然是治疗的基石，因为它具有治愈、缓解症状的潜力，并且对放射性碘治疗有良好的反应。我们报告一个极其罕见的病例，涉及一名79岁的妇女，18年前有甲状腺切除术的病史，她在Kashan Shahid Beheshti医院就诊，患有转移性甲状腺滤泡癌至颅骨。FTC的特点是早期血行性扩散，骨是典型的转移部位。在诊断为FTC的患者中，较大的肿瘤大小和骨转移的存在是预后不良的因素。然而，单独骨转移的存在不应排除积极的治疗干预。适当的管理策略可以改善患者的预后，提高患者的生活质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Radiology Case Reports Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

1.10

自引率

0.00%

发文量

1074

审稿时长

30 days

期刊介绍： The content of this journal is exclusively case reports that feature diagnostic imaging. Categories in which case reports can be placed include the musculoskeletal system, spine, central nervous system, head and neck, cardiovascular, chest, gastrointestinal, genitourinary, multisystem, pediatric, emergency, women''s imaging, oncologic, normal variants, medical devices, foreign bodies, interventional radiology, nuclear medicine, molecular imaging, ultrasonography, imaging artifacts, forensic, anthropological, and medical-legal. Articles must be well-documented and include a review of the appropriate literature.