Zihao Fan , Romain Coulon , Haoran Liu , Eric Macedo , Cong Chen
{"title":"Generation of list-mode digital dataset by Geant4 for comparison of radionuclide standardization algorithm","authors":"Zihao Fan , Romain Coulon , Haoran Liu , Eric Macedo , Cong Chen","doi":"10.1016/j.apradiso.2025.112179","DOIUrl":null,"url":null,"abstract":"<div><div>The algorithms for radionuclide standardization play a key role in accurate measurement of activity. The implementation of these algorithms requires rigorous validation to build trust and confidence in their application, which can be achieved through participation in algorithm comparisons. This work aims to generate List-Mode Digital Datasets (LMDDs) used for comparison using the Geant4 toolkit. Three models were developed based on the 4πβ(PC)-γ, 4πβ(LS)-γ, and TDCR counting systems, respectively. This paper details the data acquisition, processing, and output in simulations. Additionally, data quality assessment for LMDDs was carried out to ensure that the simulated LMDDs from the Geant4 model is reliable and suitable for algorithm comparison. Feasibility verification of these LMDDs in data analysis were performed using existing radionuclide standardization algorithms. The results demonstrate that these simulated LMDDs exhibit significant potential for application in radionuclide standardization algorithm comparison.</div></div>","PeriodicalId":8096,"journal":{"name":"Applied Radiation and Isotopes","volume":"226 ","pages":"Article 112179"},"PeriodicalIF":1.8000,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Radiation and Isotopes","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S096980432500524X","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, INORGANIC & NUCLEAR","Score":null,"Total":0}
引用次数: 0
Abstract
The algorithms for radionuclide standardization play a key role in accurate measurement of activity. The implementation of these algorithms requires rigorous validation to build trust and confidence in their application, which can be achieved through participation in algorithm comparisons. This work aims to generate List-Mode Digital Datasets (LMDDs) used for comparison using the Geant4 toolkit. Three models were developed based on the 4πβ(PC)-γ, 4πβ(LS)-γ, and TDCR counting systems, respectively. This paper details the data acquisition, processing, and output in simulations. Additionally, data quality assessment for LMDDs was carried out to ensure that the simulated LMDDs from the Geant4 model is reliable and suitable for algorithm comparison. Feasibility verification of these LMDDs in data analysis were performed using existing radionuclide standardization algorithms. The results demonstrate that these simulated LMDDs exhibit significant potential for application in radionuclide standardization algorithm comparison.
期刊介绍:
Applied Radiation and Isotopes provides a high quality medium for the publication of substantial, original and scientific and technological papers on the development and peaceful application of nuclear, radiation and radionuclide techniques in chemistry, physics, biochemistry, biology, medicine, security, engineering and in the earth, planetary and environmental sciences, all including dosimetry. Nuclear techniques are defined in the broadest sense and both experimental and theoretical papers are welcome. They include the development and use of α- and β-particles, X-rays and γ-rays, neutrons and other nuclear particles and radiations from all sources, including radionuclides, synchrotron sources, cyclotrons and reactors and from the natural environment.
The journal aims to publish papers with significance to an international audience, containing substantial novelty and scientific impact. The Editors reserve the rights to reject, with or without external review, papers that do not meet these criteria.
Papers dealing with radiation processing, i.e., where radiation is used to bring about a biological, chemical or physical change in a material, should be directed to our sister journal Radiation Physics and Chemistry.