Use of trained African giant pouched rats as a predictor of clinical diagnosis of pulmonary TB.

IF 1.6 Q4 RESPIRATORY SYSTEM

Public Health Action Pub Date : 2025-09-03 eCollection Date: 2025-09-01 DOI:10.5588/pha.25.0010

J Soka, S Mwimanzi, C D Fast, G Mwesiga, N Edward, M Stephen, R Kondo, C Cox, N Beyene, T B Agizew

引用次数: 0

Abstract

For over a decade, trained African giant pouched rats have been employed in detecting missed pulmonary TB (PTB). However, the relationship between rat-positive results and subsequent clinical PTB or extrapulmonary TB (EPTB) has not been previously reported. This report highlights the use of rat-positivity as a predictor for PTB clinical diagnosis and treatment among presumptive TB. Treating physicians were 1.39 times more likely to clinically diagnose and treat rat-positives than rat-negatives: 12% versus 9%, respectively, odds ratio=1.39, 95% confidence interval: 1.05-1.84. No difference was observed among EPTB.

Abstract Image

查看原文本刊更多论文

使用训练过的非洲巨袋大鼠作为肺结核临床诊断的预测因子。

十多年来，训练有素的非洲巨鼠被用于检测漏诊肺结核（PTB）。然而，大鼠阳性结果与随后的临床PTB或肺外结核（EPTB）之间的关系此前尚未报道。本报告强调使用大鼠阳性作为肺结核临床诊断和治疗推定结核的预测因子。治疗医生临床诊断和治疗大鼠阳性的可能性是大鼠阴性的1.39倍：分别为12%和9%，优势比=1.39,95%可信区间：1.05-1.84。EPTB间无差异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Public Health Action RESPIRATORY SYSTEM-

自引率

0.00%

发文量

期刊介绍： Launched on 1 May 2011, Public Health Action (PHA) is an official publication of the International Union Against Tuberculosis and Lung Disease (The Union). It is an open access, online journal available world-wide to physicians, health workers, researchers, professors, students and decision-makers, including public health centres, medical, university and pharmaceutical libraries, hospitals, clinics, foundations and institutions. PHA is a peer-reviewed scholarly journal that actively encourages, communicates and reports new knowledge, dialogue and controversy in health systems and services for people in vulnerable and resource-limited communities — all topics that reflect the mission of The Union, Health solutions for the poor.