Nataša R Mijailović, Maja Milojević-Rakić, Katarina Mihajlović
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引用次数: 0
Abstract
Depression is a common psychiatric condition with a considerable influence on global health. Although current pharmacotherapeutic choices are of indisputable relevance, there is sustained interest in natural medicines for treating depressive symptoms. Polyphenols, a class of plant-derived natural compounds, have received attention due to their possible neuroprotective and anti-depressive properties. In this review, we aimed to present the intricate mechanisms through which polyphenols modulate inflammation, neurogenesis, oxidative stress, and the gut microbiota. Consumption of polyphenol-rich diets is emerging as a non-invasive, natural, and cost-effective approach to supporting brain health, with potential influence on depressive symptoms. While there have been promising results, more research is needed to draw solid conclusions regarding the medicinal potential of polyphenols.
期刊介绍：
The World Journal of Psychiatry (WJP) is a high-quality, peer reviewed, open-access journal. The primary task of WJP is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of psychiatry. In order to promote productive academic communication, the peer review process for the WJP is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJP are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in psychiatry.
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