Long-Term Outcomes of Congenital Biliary Dilatation Surgery: A Single-Center Study Highlighting the High Incidence of Complications Within 5 Years.

IF 2.8 3区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY
Takuya Maeda, Hiroo Uchida, Chiyoe Shirota, Takahisa Tainaka, Satoshi Makita, Hajime Asai, Ami Utsunomiya, Yui Murata, Yaohui Guo, Jiahui Liu
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引用次数: 0

Abstract

Background: Congenital biliary dilatation (CBD) is a rare anomaly often treated surgically, yet postoperative complications remain a concern. This study aimed to evaluate the incidence, timing, and risk factors of such complications after CBD surgery.

Methods: A retrospective review was conducted on 184 patients with CBD who underwent either open or laparoscopic surgery, with a mean follow-up of 9 years. The analysis focused on postoperative complications, including bile duct-related issues, pancreatic complications, and bowel obstruction.

Results: Complications occurred in 14.7% of patients, predominantly bile duct-related (11.4%), followed by pancreatic (1.6%) and bowel obstruction (1.6%). Most bile duct complications, including anastomotic and intrahepatic strictures, emerged within 5 years postoperatively. Residual bile ducts were more common after open surgery, but no significant difference in other complications was observed between surgical approaches. No biliary malignancies developed during follow-up.

Conclusion: The majority of complications occurred within 5 years after surgery, underscoring the importance of intensive monitoring during this period. Regular imaging and blood tests are essential for early detection. Although no malignancies were observed, long-term follow-up remains critical to address late-onset risks.

Trial registration: Clinical registration number: 2023-045432262.

先天性胆道扩张手术的长期预后:一项强调5年内并发症高发的单中心研究。
背景:先天性胆道扩张(CBD)是一种罕见的异常,通常通过手术治疗,但术后并发症仍然令人担忧。本研究旨在评估CBD手术后此类并发症的发生率、时间和危险因素。方法:对184例接受开放或腹腔镜手术的CBD患者进行回顾性分析,平均随访9年。分析的重点是术后并发症,包括胆管相关问题、胰腺并发症和肠梗阻。结果:14.7%的患者发生并发症,以胆管相关(11.4%)为主,其次为胰腺(1.6%)和肠梗阻(1.6%)。大多数胆管并发症,包括吻合口和肝内狭窄,在术后5年内出现。胆管残留在开放手术后更为常见,但其他并发症在两种手术入路间无显著差异。随访期间无胆道恶性肿瘤发生。结论:并发症主要发生在术后5年内,这一时期应加强监测。定期影像学检查和血液检查对于早期发现至关重要。虽然没有观察到恶性肿瘤,长期随访仍然是解决迟发性风险的关键。试验注册:临床注册号:2023-045432262。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Hepato‐Biliary‐Pancreatic Sciences
Journal of Hepato‐Biliary‐Pancreatic Sciences GASTROENTEROLOGY & HEPATOLOGY-SURGERY
自引率
10.00%
发文量
178
审稿时长
6-12 weeks
期刊介绍: The Journal of Hepato-Biliary-Pancreatic Sciences (JHBPS) is the leading peer-reviewed journal in the field of hepato-biliary-pancreatic sciences. JHBPS publishes articles dealing with clinical research as well as translational research on all aspects of this field. Coverage includes Original Article, Review Article, Images of Interest, Rapid Communication and an announcement section. Letters to the Editor and comments on the journal’s policies or content are also included. JHBPS welcomes submissions from surgeons, physicians, endoscopists, radiologists, oncologists, and pathologists.
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